MAOA

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Monoamine oxidase A
PDB rendering based on 2bxr.
Available structures: 2bxr, 2bxs
Identifiers
Symbol(s)	MAOA;
External IDs	OMIM: 309850 MGI: 96915 HomoloGene: 203
EC number	1.4.3.4
Gene ontology Molecular Function: • amine oxidase activity • oxidoreductase activity Cellular Component: • mitochondrion • membrane • integral to membrane Biological Process: • electron transport • catecholamine metabolic process • behavior • dopamine catabolic process
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	4128	17161
Ensembl	ENSG00000189221	ENSMUSG00000025037
Uniprot	P21397	Q3TPD9
Refseq	NM_000240 (mRNA) NP_000231 (protein)	NM_173740 (mRNA) NP_776101 (protein)
Location	Chr X: 43.4 - 43.49 Mb	Chr X: 15.78 - 15.84 Mb
Pubmed search	[1]	[2]

Monoamine oxidase A, also known as MAOA, is a human gene.

This gene encodes monoamine oxidase A, an enzyme that degrades amine neurotransmitters, such as dopamine, norepinephrine, and serotonin. The protein localizes to the mitochondrial outer membrane. The gene is adjacent to a related gene on the opposite strand of chromosome X. Mutation in this gene results in monoamine oxidase deficiency, or Brunner syndrome.^[1]

[edit] See also

• Monoamine oxidase

[edit] References

[edit] Further reading