Mandelamide amidase

From Wikipedia, the free encyclopedia

In enzymology, a mandelamide amidase (EC 3.5.1.86) is an enzyme that catalyzes the chemical reaction

(R)-mandelamide + H₂O (R)-mandelate + NH₃

Thus, the two substrates of this enzyme are (R)-mandelamide and H₂O, whereas its two products are (R)-mandelate and NH₃.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is mandelamide hydrolase. This enzyme is also called Pseudomonas mandelamide hydrolase.

[edit] References

• IUBMB entry for 3.5.1.86
• BRENDA references for 3.5.1.86 (Recommended.)
• PubMed references for 3.5.1.86
• PubMed Central references for 3.5.1.86
• Google Scholar references for 3.5.1.86
• Yamamoto K, Oishi K, Fujimatsu I, Komatsu K (1991). "Production of R-(-)-mandelic acid from mandelonitrile by Alcaligenes faecalis ATCC 8750". Appl. Environ. Microbiol. 57: 3028–32. PMID 1660699. 

[edit] External links

• IUBMB entry for 3.5.1.86

• KEGG entry for 3.5.1.86

• BRENDA entry for 3.5.1.86

• NiceZyme view of 3.5.1.86

• EC2PDB: PDB structures for 3.5.1.86

• PRIAM entry for 3.5.1.86

• PUMA2 entry for 3.5.1.86

• IntEnz: Integrated Enzyme entry for 3.5.1.86

• MetaCyc entry for 3.5.1.86

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050537: mandelamide amidase

• AMIGO entry for GO code 0050537: mandelamide amidase