Magaldrate

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Magaldrate
Systematic (IUPAC) name
Magnesium aluminate monohydrate
Identifiers
CAS number	1317-26-6
ATC code	A02AD02 A02AF01
PubChem	6336542
Chemical data
Formula	H3O2-
Mol. mass	86.3092 g/mol
Pharmacokinetic data
Bioavailability	Negligible
Metabolism	Nil
Half life	?
Excretion	Fecal and renal
Therapeutic considerations
Pregnancy cat.	C
Legal status	OTC
Routes	Oral

Magaldrate (INN), is a common antiacid drug that is used for the treatment of duodenal and gastric ulcers, esophagitis from gastroesophageal reflux.

Contents 1 Formula 2 Available forms 3 Interactions and adverse reactions 4 Brand names

[edit] Formula

Al₅Mg₁₀(OH)₃₁(SO₄)₂ H₂O

[edit] Available forms

Magaldrate is available in the form of oral suspension or tablets.

[edit] Interactions and adverse reactions

Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.

[edit] Brand names

The drug is sold with the following brand names:

• Gradal (Italy);
• Magaltop (Italy);
• Magralibi (Italy);
• Riopan (Argentina, Austria, Brazil, Germany, Italy, belgium).