Lung cancer surgery

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Lung cancer surgery describes the use of surgical operations in the treatment of lung cancer. It involves the surgical excision of cancer tissue from the lung. It is used mainly in non-small cell lung cancer with the intention of curing the patient.

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[edit] Patient selection

Not all patients are suitable for operation. The stage, location and cell type are important limiting factors. In addition, patients who are very ill with a poor performance status or who have inadequate pulmonary reserve would be unlikely to survive. Even with careful selection, the overall operative death rate is about 4.4%.[1]

[edit] Stage

"Stage" refers to the degree of spread of the cancer.

See non-small cell lung cancer staging

In non-small cell lung cancer, stages IA, IB, IIA, and IIB are suitable for surgical resection.[2]

[edit] Pulmonary reserve

Pulmonary reserve is measured by spirometry. The minimum forced vital capacity (FVC) for pneumonectomy in men is 2 liters. The minimum for lobectomy is 1.5 liters. In women, the minimum FVC values for pneumonectomy and lobectomy are 1.75 liters and 1.25 liters respectively.[3]

[edit] Types of surgery

  • Lobectomy (removal of a lobe of the lung)[4]
  • Segmentectomy (removal of an anatomic division of a particular lobe of the lung)
  • Pneumonectomy (removal of an entire lung)
  • Wedge resection
  • Sleeve/bronchoplastic resection (removal of an associated tubular section of the associated main bronchial passage during lobectomy with subsequent reconstruction of the bronchial passage)

[edit] References

  1. ^ Strand, TE; Rostad H, Damhuis RA, Norstein J (Jun 2007). "Risk factors for 30-day mortality after resection of lung cancer and prediction of their magnitude". Thorax. BMJ Publishing Group Ltd.. PMID 17573442. 
  2. ^ Mountain, CF (1997). "Revisions in the international system for staging lung cancer". Chest 111: 1710–1717. American College of Chest Physicians. 
  3. ^ Schirren, J; Krysa S, Trainer S et al. (1995). "Surgical treatment and results. Carcinoma of the lung". The European Respiratory Monograph 1 (1): 212–240. 
  4. ^ Fell, SC; TJ Kirby (2005). General Thoracic Surgery, sixth edition, Lippincott Williams & Wilkins, 433–457. ISBN 0-7817-3889-X. 


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