Talk:Loratadine
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Wasn't there some big scandal several years ago about how Claritin only worked on about 51% of the people used it? --User:Arm
- Never heard of it. I doubt that's possible. I just know around cats I mine as well die and claritin makes LAN parties possible - or if I have housecalls for work, I have to run and grab a claritin asap - or the homeowner will think I have a terrible flu.--x1987x(talk) 22:47, 7 May 2006 (UTC)
- Yes, Arm is right. I've added a link to a New York Times Magazine article from 2001 that talks about that, and I've added some discussion of its effectiveness to the article.--76.81.180.3 03:00, 17 August 2007 (UTC)
Also, is there any difference in chemical makeup between Claritin© and Claritin-D©? It'd just be helpful information for the article. MToolen 22:38, 15 January 2006 (UTC)
- Claritin just contains loratadine. Claritin-D also includes 240mg of time-release pseudoephedrine. Haikupoet 23:58, 15 January 2006 (UTC)
The link "Lek" inside Wikipedia did not lead neither to pharmaceutical company "Lek" nor to "Sandoz", whose part it is now. I added a line about it on disambiguation page.
Says "doesn't cause drowsiness" but in the side-effects it says "drowsiness"
- In normal doses it doesn't -- apparently it's fairly poor at crossing the blood-brain barrier or something like that. You have to overdose on it to get a sedative effect. Haikupoet 04:41, 14 May 2006 (UTC)
- Haikupoet, it's not quite accurate to say that you have to "overdose" to get a sedative effect. "Overdose" implies using a very large, harmful amount. Actually the history of the drug's development was that 10 mg was the highest dose at which it seemed to be nonsedating. At 20 mg, it is both more effective and somewhat sedating, but I wouldn't apply the term "overdose" to that dosage. Also, the sedative effect may vary from person to person.--76.81.180.3 02:58, 17 August 2007 (UTC)
- Also note that the side effects of dry mouth, GI disturbance and drowsiness are listed in the side effects of almost every drug sold. In fact, in several studies even placebo has these "side effects." the concensus is that these "side effects" are common everyday feelings that people get and are unrelated to the drugs. how often do you how upset stomachs or feel tired? 69.160.209.33 20:30, 21 June 2006 (UTC)
Quote: "In the U.S. and UK loratadine is the only drug of its class available over the counter." it is controversial. Assuming Loratadine as a systemic anti-hystamine with standard allergy relief properties, the product Cetirizine is also classed as GSL in the UK. I suggest rephrasing or correcting.--nicowalker 15:53, 5 April 2007 (UTC)
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[edit] Korea and foreign names
The name in Korea is 로라타딘 but I'm not sure where it should go in the article. --Gbleem 06:04, 10 December 2006 (UTC)
Super Callum! xxx 08:38, 24 April 2007 (UTC) I edited it to describe the availability in the UK - In my store, packs of up to seven can be sold normally, whereas larger packs must be sold - as with all "P Line" medicines - by a pharmacist.
[edit] Cautions and contraindications
In this section, it says this is a Class B pregnancy drug, yet the article linked in source 7 says that it is Class C. Which is correct? Elizabeb (talk) 19:03, 17 May 2008 (UTC)
[edit] Don't understand...
"Reviewing a randomized, double-blind trial, Dr. Sherwin D. Straus of the FDA argued at one point that "10 milligrams is not very different than placebo clinically," and that the reason for making the dose so low was that at higher, more effective doses, it became sedating."
Does this not just say that the drug is ineffective? Why was it approved at this dosage that is ineffective just so they can put a "non-drowsy" label on it? This is just further proof of the corruption and ineffectiveness of the FDA. Billions were made, million were deceived and their money taken in fraud and false advertising. Yeah FDA!
[edit] Don't understand...
"Reviewing a randomized, double-blind trial, Dr. Sherwin D. Straus of the FDA argued at one point that "10 milligrams is not very different than placebo clinically," and that the reason for making the dose so low was that at higher, more effective doses, it became sedating."
Does this not just say that the drug is ineffective? Why was it approved at this dosage that is ineffective just so they can put a "non-drowsy" label on it? This is just further proof of the corruption and ineffectiveness of the FDA. Billions were made, million were deceived and their money taken in fraud and false advertising. Yeah FDA!
Coop2112 (talk) 14:32, 21 May 2008 (UTC)
