Loewe additivity

From Wikipedia, the free encyclopedia

 The introduction to this June 2007 provides insufficient context for those unfamiliar with the subject.
Please help improve the article with a good introductory style.

Loewe additivity is one several common reference models used for measuring the effects of drug combinations.

Loewe additivity is based on the idea that an agent should not have synergistic interactions with itself.

[edit] References

  • William R Greco, Gregory Bravo, and John Parsons "The Search for Synergy: A Critical Review from a Response Surface Perspective", Pharmacological Reviews 47(2) 331-385 (1995)
  • Loewe and Muischnek. "Effect of combinations: mathematical basis of the problem" Arch. Exp. Pathol. Pharmakol. 114: 313-326, 1926
Tablets  This pharmacology-related article is a stub. You can help Wikipedia by expanding it.