Lipoamide
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| Lipoamide | |
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| Identifiers | |
| CAS number | [940-69-2] |
| PubChem | |
| MeSH | |
| SMILES | NC(=O)CCCC[C@@H]1CCSS1 |
| Properties | |
| Molecular formula | C8H15NOS2 |
| Molar mass | 205.343 g/mol |
| Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references |
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Lipoamide is a trivial name for 6,8-dithiooctanoic amide. It is 6,8-dithiooctanoic acid's functional form where the carboxyl group is attached to protein (or any other amine) by an amide linkage (containing -NH2) to an amino group.
Lipoamide forms a thioester bond, oxidizing the disulfide bond, with acetaldehyde (pyruvate after it has been decarboxylated). It then transfer the acetaldehyde group to CoA which can then continue in the TCA cycle.
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