LIN7B

From Wikipedia, the free encyclopedia

Lin-7 homolog B (C. elegans)

PDB rendering based on 1y74.

Available structures: 1y74, 2dkr

Identifiers

Symbol(s)

LIN7B; LIN-7B; MALS-2; VELI2

External IDs

MGI: 1330858 HomoloGene: 22648

Gene ontology
Molecular Function:	• protein binding
Cellular Component:	• plasma membrane • tight junction • synaptosome • synapse
Biological Process:	• exocytosis • neurotransmitter secretion • protein transport

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_022165 (mRNA)
NP_071448 (protein)

XM_001002360 (mRNA)
XP_001002360 (protein)

Location

Chr 19: 54.31 - 54.31 Mb

Chr 7: 45.24 - 45.24 Mb

Pubmed search

[1]

[2]

Lin-7 homolog B (C. elegans), also known as LIN7B, is a human gene.^[1]

[edit] References

^ Entrez Gene: LIN7B lin-7 homolog B (C. elegans).

[edit] Further reading

Butz S, Okamoto M, Südhof TC (1998). "A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.". Cell 94 (6): 773-82. PMID 9753324.
Jo K, Derin R, Li M, Bredt DS (1999). "Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex.". J. Neurosci. 19 (11): 4189-99. PMID 10341223.
Olsen O, Liu H, Wade JB, et al. (2002). "Basolateral membrane expression of the Kir 2.3 channel is coordinated by PDZ interaction with Lin-7/CASK complex.". Am. J. Physiol., Cell Physiol. 282 (1): C183-95. doi:10.1152/ajpcell.00249.2001. PMID 11742811.
Coussen F, Normand E, Marchal C, et al. (2002). "Recruitment of the kainate receptor subunit glutamate receptor 6 by cadherin/catenin complexes.". J. Neurosci. 22 (15): 6426-36. doi:20026623. PMID 12151522.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309.
Hori K, Konno D, Maruoka H, Sobue K (2003). "MALS is a binding partner of IRSp53 at cell-cell contacts.". FEBS Lett. 554 (1-2): 30-4. PMID 14596909.
Leonoudakis D, Conti LR, Radeke CM, et al. (2004). "A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.". J. Biol. Chem. 279 (18): 19051-63. doi:10.1074/jbc.M400284200. PMID 14960569.
Leonoudakis D, Conti LR, Anderson S, et al. (2004). "Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.". J. Biol. Chem. 279 (21): 22331-46. doi:10.1074/jbc.M400285200. PMID 15024025.
Hruska-Hageman AM, Benson CJ, Leonard AS, et al. (2004). "PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current.". J. Biol. Chem. 279 (45): 46962-8. doi:10.1074/jbc.M405874200. PMID 15317815.
Okuhira K, Fitzgerald ML, Sarracino DA, et al. (2006). "Purification of ATP-binding cassette transporter A1 and associated binding proteins reveals the importance of beta1-syntrophin in cholesterol efflux.". J. Biol. Chem. 280 (47): 39653-64. doi:10.1074/jbc.M510187200. PMID 16192269.
Kawai S, Fukuda C, Mukai T, Murata K (2006). "MJ0917 in archaeon Methanococcus jannaschii is a novel NADP phosphatase/NAD kinase.". J. Biol. Chem. 280 (47): 39200-7. doi:10.1074/jbc.M506426200. PMID 16192277.
Li Z, Benard O, Margolskee RF (2006). "Ggamma13 interacts with PDZ domain-containing proteins.". J. Biol. Chem. 281 (16): 11066-73. doi:10.1074/jbc.M600113200. PMID 16473877.
Sudo K, Ito H, Iwamoto I, et al. (2007). "Identification of a cell polarity-related protein, Lin-7B, as a binding partner for a Rho effector, Rhotekin, and their possible interaction in neurons.". Neurosci. Res. 56 (4): 347-55. doi:10.1016/j.neures.2006.08.003. PMID 16979770.