LGALS3

Lectin, galactoside-binding, soluble, 3

PDB rendering based on 1a3k.

Available structures: 1a3k, 1kjl, 1kjr, 2nmn, 2nmo, 2nn8

Identifiers

Symbol(s)

LGALS3; LGALS2; CBP35; GAL3; GALBP; GALIG; MAC2

External IDs

Gene ontology
Molecular Function:	• protein binding • sugar binding • IgE binding
Cellular Component:	• extracellular region • proteinaceous extracellular matrix • nucleus • cytoplasm • plasma membrane
Biological Process:	• skeletal development • extracellular matrix organization and biogenesis

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_194327 (mRNA)
NP_919308 (protein)

NM_010705 (mRNA)
NP_034835 (protein)

Location

Pubmed search

Lectin, galactoside-binding, soluble, 3, also known as LGALS3, is a human gene.^[1]

[edit] See also

Barondes SH, Cooper DN, Gitt MA, Leffler H (1994). "Galectins. Structure and function of a large family of animal lectins.". J. Biol. Chem. 269 (33): 20807–10. PMID 8063692.
Nakahara S, Oka N, Raz A (2005). "On the role of galectin-3 in cancer apoptosis.". Apoptosis 10 (2): 267–75. doi:10.1007/s10495-005-0801-y. PMID 15843888.
Fukumori T, Kanayama HO, Raz A (2007). "The role of galectin-3 in cancer drug resistance.". Drug Resist. Updat. 10 (3): 101–8. doi:10.1016/j.drup.2007.04.001. PMID 17544840.