LGALS1

From Wikipedia, the free encyclopedia

Lectin, galactoside-binding, soluble, 1 (galectin 1)
PDB rendering based on 1gzw.
Available structures: 1gzw, 1w6m, 1w6n, 1w6o, 1w6p, 1w6q
Identifiers
Symbol(s)	LGALS1; GBP; DKFZp686E23103
External IDs	OMIM: 150570 MGI: 96777 HomoloGene: 7399
Gene ontology Molecular Function: • signal transducer activity • sugar binding Cellular Component: • extracellular space • intracellular • cytoplasm Biological Process: • regulation of apoptosis • positive regulation of I-kappaB kinase/NF-kappaB cascade • myoblast differentiation
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	3956	16852
Ensembl	ENSG00000100097	ENSMUSG00000068220
Uniprot	P09382	P16045
Refseq	NM_002305 (mRNA) NP_002296 (protein)	NM_008495 (mRNA) NP_032521 (protein)
Location	Chr 22: 36.4 - 36.41 Mb	Chr 15: 78.75 - 78.76 Mb
Pubmed search	[1]	[2]

Lectin, galactoside-binding, soluble, 1 (galectin 1), also known as LGALS1, is a human gene.

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS1 may act as an autocrine negative growth factor that regulates cell proliferation.^[1]

[edit] See also

• Galectin

[edit] References

[edit] Further reading