Levansucrase

From Wikipedia, the free encyclopedia

In enzymology, a levansucrase (EC 2.4.1.10) is an enzyme that catalyzes the chemical reaction

sucrose + (2,6-beta-D-fructosyl)n $\rightleftharpoons$ glucose + (2,6-beta-D-fructosyl)n⁺1

Thus, the two substrates of this enzyme are sucrose and (2,6-beta-D-fructosyl)n, whereas its two products are glucose and (2,6-beta-D-fructosyl)n+1.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:2,6-beta-D-fructan 6-beta-D-fructosyltransferase. Other names in common use include sucrose 6-fructosyltransferase, beta-2,6-fructosyltransferase, and beta-2,6-fructan:D-glucose 1-fructosyltransferase. This enzyme participates in starch and sucrose metabolism and two-component system - general.

1 Structural studies
2 References
3 External links
- 3.1 Gene Ontology (GO) codes

[edit] Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes 1OYG, 1PT2, and 1W18.

[edit] References

IUBMB entry for 2.4.1.10
BRENDA references for 2.4.1.10 (Recommended.)
PubMed references for 2.4.1.10
PubMed Central references for 2.4.1.10
Google Scholar references for 2.4.1.10
Hehre EJ (1951). "Enzymic synthesis of polysaccharides: a biological type of polymerization". Adv. Enzymol. Relat. Subj. Biochem. 11: 297–337.
AVIGAD G, FEINGOLD DS, HESTRIN S (1956). "The mechanism of polysaccharide production from sucrose. 3 Donor-acceptor specificity of levansucrase from Aerobacter levanicum". Biochem. J. 64: 340–51. PMID 13363847.
Reese ET, Avigad G (1966). "Purification of levansucrase by precipitation with levan". Biochim. Biophys. Acta. 113: 79–83. PMID 5940635.