Leucine N-acetyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a leucine N-acetyltransferase (EC 2.3.1.66) is an enzyme that catalyzes the chemical reaction

acetyl-CoA + L-leucine CoA + N-acetyl-L-leucine

Thus, the two substrates of this enzyme are acetyl-CoA and L-leucine, whereas its two products are CoA and N-acetyl-L-leucine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acetyl-CoA:L-leucine N-acetyltransferase. This enzyme is also called leucine acetyltransferase.

[edit] References

• IUBMB entry for 2.3.1.66
• BRENDA references for 2.3.1.66 (Recommended.)
• PubMed references for 2.3.1.66
• PubMed Central references for 2.3.1.66
• Google Scholar references for 2.3.1.66
• Suzukake S, Hayashi H, Hori M and Umezawa H (1982). "Biosnthesis of leupeptin III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine". J. Antibiot. 33: 857–862. 

[edit] External links

The CAS registry number for this enzyme class is 75496-56-9.

• IUBMB entry for 2.3.1.66

• KEGG entry for 2.3.1.66

• BRENDA entry for 2.3.1.66

• NiceZyme view of 2.3.1.66

• EC2PDB: PDB structures for 2.3.1.66

• PRIAM entry for 2.3.1.66

• PUMA2 entry for 2.3.1.66

• IntEnz: Integrated Enzyme entry for 2.3.1.66

• MetaCyc entry for 2.3.1.66

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0050050: leucine N-acetyltransferase

• AMIGO entry for GO code 0050050: leucine N-acetyltransferase