Langerin

From Wikipedia, the free encyclopedia

Langerin is a type II transmembrane cell surface receptor produced by Langerhans cells.

Langerin on mucosal Langerhans cells in the lining of human genitalia was shown in 2007 to have a destructive effect on HIV.

[edit] See also

• Paul Langerhans
• Langerhans cell

[edit] External links

• Langerin is a natural barrier to HIV-1 transmission by Langerhans cells (de Witte et al.)
• The role of dendritic cell C-type lectin receptors in HIV pathogenesis (Turville et al.)
• Langerin, a novel C-type lectin specific to Langerhans cells, is an endocytic receptor that induces the formation of Birbeck granules (Valladeau et al.)
• Identification of Mouse Langerin/CD207 in Langerhans Cells and Some Dendritic Cells of Lymphoid Tissues (Valladeau et al.)

v • d • e Protein: lectins animal Calnexin - Calreticulin - CD22 - CD33 - Galectin - Myelin-associated glycoprotein - N-Acetylglucosamine receptor - Selectin - Sialoadhesin animal, calcium-dependent Aggrecan - Asialoglycoprotein receptor - CD94 - Collectin (Mannan-binding lectin) - Mannose receptor - Versican plant Abrin - Ricin - Mitogens (Concanavalin A, Phytohaemagglutinin, Pokeweed mitogen) - Legume lectin