LAD1

From Wikipedia, the free encyclopedia


Ladinin 1
Identifiers
Symbol(s) LAD1; LadA; MGC10355
External IDs OMIM: 602314 MGI: 109343 HomoloGene: 4059
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 3898 16763
Ensembl ENSG00000159166 ENSMUSG00000041782
Uniprot O00515 Q8R3D5
Refseq XM_001134298 (mRNA)
XP_001134298 (protein)		 NM_133664 (mRNA)
NP_598425 (protein)
Location Chr 1: 199.62 - 199.64 Mb Chr 1: 137.64 - 137.65 Mb
Pubmed search [1] [2]

Ladinin 1, also known as LAD1, is a human gene.[1]

The protein encoded by this gene may be an anchoring filament that is a component of basement membranes. It may contribute to the stability of the association of the epithelial layers with the underlying mesenchyme.[1]

[edit] References

  1. ^ a b Entrez Gene: LAD1 ladinin 1.

[edit] Further reading

  • Uitto J, Pulkkinen L (1997). "Molecular complexity of the cutaneous basement membrane zone.". Mol. Biol. Rep. 23 (1): 35-46. PMID 8983017. 
  • Kim JE, Tannenbaum SR, White FM (2005). "Global phosphoproteome of HT-29 human colon adenocarcinoma cells.". J. Proteome Res. 4 (4): 1339-46. doi:10.1021/pr050048h. PMID 16083285. 
  • Benzinger A, Muster N, Koch HB, et al. (2005). "Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.". Mol. Cell Proteomics 4 (6): 785-95. doi:10.1074/mcp.M500021-MCP200. PMID 15778465. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Shimizu H, Takizawa Y, Pulkkinen L, et al. (1998). "The 97 kDa linear IgA bullous dermatosis antigen is not expressed in a patient with generalized atrophic benign epidermolysis bullosa with a novel homozygous G258X mutation in COL17A1.". J. Invest. Dermatol. 111 (5): 887-92. doi:10.1046/j.1523-1747.1998.00363.x. PMID 9804354. 
  • Ishiko A, Shimizu H, Masunaga T, et al. (1998). "97 kDa linear IgA bullous dermatosis antigen localizes in the lamina lucida between the NC16A and carboxyl terminal domains of the 180 kDa bullous pemphigoid antigen.". J. Invest. Dermatol. 111 (1): 93-6. doi:10.1046/j.1523-1747.1998.00231.x. PMID 9665393. 
  • Motoki K, Megahed M, LaForgia S, Uitto J (1997). "Cloning and chromosomal mapping of mouse ladinin, a novel basement membrane zone component.". Genomics 39 (3): 323-30. doi:10.1006/geno.1996.4507. PMID 9119369. 
  • Ishiko A, Shimizu H, Masunaga T, et al. (1996). "97-kDa linear IgA bullous dermatosis (LAD) antigen localizes to the lamina lucida of the epidermal basement membrane.". J. Invest. Dermatol. 106 (4): 739-43. PMID 8618014. 
  • Marinkovich MP, Taylor TB, Keene DR, et al. (1996). "LAD-1, the linear IgA bullous dermatosis autoantigen, is a novel 120-kDa anchoring filament protein synthesized by epidermal cells.". J. Invest. Dermatol. 106 (4): 734-8. PMID 8618013. 
 This article on a gene on chromosome 1 is a stub. You can help Wikipedia by expanding it.