L-2-amino-4-chloropent-4-enoate dehydrochlorinase

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In enzymology, a L-2-amino-4-chloropent-4-enoate dehydrochlorinase (EC 4.5.1.4) is an enzyme that catalyzes the chemical reaction

L-2-amino-4-chloropent-4-enoate + H₂O 2-oxopent-4-enoate + chloride + NH₃

Thus, the two substrates of this enzyme are L-2-amino-4-chloropent-4-enoate and H₂O, whereas its 3 products are 2-oxopent-4-enoate, chloride, and NH₃.

This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. The systematic name of this enzyme class is L-2-amino-4-chloropent-4-enoate chloride-lyase (adding H2O deaminating; 2-oxopent-4-enoate-forming). Other names in common use include L-2-amino-4-chloro-4-pentenoate dehalogenase, and L-2-amino-4-chloropent-4-enoate chloride-lyase (deaminating).

[edit] References

• IUBMB entry for 4.5.1.4
• BRENDA references for 4.5.1.4 (Recommended.)
• PubMed references for 4.5.1.4
• PubMed Central references for 4.5.1.4
• Google Scholar references for 4.5.1.4
• Moriguchi M, Hoshino S and Hatanaka S-I (1987). "Dehalogenation and deamination of l-2-amino-4-chloro-4-pentenoic acid by Proteus mirabilis". Agric. Biol. Chem. 51: 3295. 

[edit] External links

The CAS registry number for this enzyme class is 113066-37-8.

• IUBMB entry for 4.5.1.4

• KEGG entry for 4.5.1.4

• BRENDA entry for 4.5.1.4

• NiceZyme view of 4.5.1.4

• EC2PDB: PDB structures for 4.5.1.4

• PRIAM entry for 4.5.1.4

• PUMA2 entry for 4.5.1.4

• IntEnz: Integrated Enzyme entry for 4.5.1.4

• MetaCyc entry for 4.5.1.4

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047460: L-2-amino-4-chloropent-4-enoate dehydrochlorinase

• AMIGO entry for GO code 0047460: L-2-amino-4-chloropent-4-enoate dehydrochlorinase