KRT33A

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Keratin 33A
Identifiers
Symbol(s) KRT33A; HA3I; Ha-3I; KRTHA3A; Krt1-3; hHa3-I
External IDs OMIM: 602761 MGI: 1919138 HomoloGene: 68245
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 3883 71888
Ensembl ENSG00000006059 n/a
Uniprot O76009 n/a
Refseq NM_004138 (mRNA)
NP_004129 (protein)		 NM_027983 (mRNA)
NP_082259 (protein)
Location Chr 17: 36.76 - 36.76 Mb n/a
Pubmed search [1] [2]

Keratin 33A, also known as KRT33A, is a human gene.[1]

The protein encoded by this gene is a member of the keratin gene family. It is one of the type I hair keratin genes which are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. There are two isoforms of this protein, encoded by two separate genes, KRTHA3A and KRTHA3B.[1]

[edit] References

  1. ^ a b Entrez Gene: KRT33A keratin 33A.

[edit] Further reading

  • Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S-59S. PMID 7686952. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
  • Schweizer J, Bowden PE, Coulombe PA, et al. (2006). "New consensus nomenclature for mammalian keratins.". J. Cell Biol. 174 (2): 169-74. doi:10.1083/jcb.200603161. PMID 16831889. 
  • Rogers MA, Winter H, Langbein L, et al. (2005). "The human type I keratin gene family: characterization of new hair follicle specific members and evaluation of the chromosome 17q21.2 gene domain.". Differentiation 72 (9-10): 527-40. doi:10.1111/j.1432-0436.2004.07209006.x. PMID 15617563. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874-84. PMID 10391933. 
  • Rogers MA, Winter H, Wolf C, et al. (1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes.". J. Biol. Chem. 273 (41): 26683-91. PMID 9756910. 
  • Rogers MA, Schweizer J, Kreig T, Winter H (1995). "A novel human type I hair keratin gene: evidence for two keratin hHa3 isoforms.". Mol. Biol. Rep. 20 (3): 155-61. PMID 7565656. 
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