KRT32

From Wikipedia, the free encyclopedia


Keratin 32
Identifiers
Symbol(s) KRT32; HA2; HKA2; KRTHA2; hHa2
External IDs OMIM: 602760 MGI1309995 HomoloGene68246
RNA expression pattern

More reference expression data

Orthologs
Human Mouse
Entrez 3882 16670
Ensembl ENSG00000108759 ENSMUSG00000046095
Uniprot Q14532 Q148N4
Refseq NM_002278 (mRNA)
NP_002269 (protein)
NM_010665 (mRNA)
NP_034795 (protein)
Location Chr 17: 36.87 - 36.88 Mb Chr 11: 99.9 - 99.9 Mb
Pubmed search [1] [2]

Keratin 32, also known as KRT32, is a human gene.[1]

The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[1]

[edit] References

[edit] Further reading

  • Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S-59S. PMID 7686952. 
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931. 
  • Schweizer J, Bowden PE, Coulombe PA, et al. (2006). "New consensus nomenclature for mammalian keratins.". J. Cell Biol. 174 (2): 169-74. doi:10.1083/jcb.200603161. PMID 16831889. 
  • Adkins JN, Varnum SM, Auberry KJ, et al. (2003). "Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.". Mol. Cell Proteomics 1 (12): 947-55. PMID 12543931. 
  • Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874-84. PMID 10391933. 
  • Rogers MA, Winter H, Langbein L, et al. (1996). "Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5.". J. Invest. Dermatol. 107 (4): 633-8. PMID 8823373. 
  • Rogers MA, Nischt R, Korge B, et al. (1995). "Sequence data and chromosomal localization of human type I and type II hair keratin genes.". Exp. Cell Res. 220 (2): 357-62. doi:10.1006/excr.1995.1326. PMID 7556444. 
  • Heid HW, Moll I, Franke WW (1988). "Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles.". Differentiation 37 (2): 137-57. PMID 2456239.