KRT32
From Wikipedia, the free encyclopedia
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Keratin 32
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| Identifiers | ||||||||||||||
| Symbol(s) | KRT32; HA2; HKA2; KRTHA2; hHa2 | |||||||||||||
| External IDs | OMIM: 602760 MGI: 1309995 HomoloGene: 68246 | |||||||||||||
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| RNA expression pattern | ||||||||||||||
| Orthologs | ||||||||||||||
| Human | Mouse | |||||||||||||
| Entrez | 3882 | 16670 | ||||||||||||
| Ensembl | ENSG00000108759 | ENSMUSG00000046095 | ||||||||||||
| Uniprot | Q14532 | Q148N4 | ||||||||||||
| Refseq | NM_002278 (mRNA) NP_002269 (protein) |
NM_010665 (mRNA) NP_034795 (protein) |
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| Location | Chr 17: 36.87 - 36.88 Mb | Chr 11: 99.9 - 99.9 Mb | ||||||||||||
| Pubmed search | [1] | [2] | ||||||||||||
Keratin 32, also known as KRT32, is a human gene.[1]
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.[1]
[edit] References
[edit] Further reading
- Yu J, Yu DW, Checkla DM, et al. (1993). "Human hair keratins.". J. Invest. Dermatol. 101 (1 Suppl): 56S-59S. PMID 7686952.
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:. PMID 17353931.
- Schweizer J, Bowden PE, Coulombe PA, et al. (2006). "New consensus nomenclature for mammalian keratins.". J. Cell Biol. 174 (2): 169-74. doi:. PMID 16831889.
- Adkins JN, Varnum SM, Auberry KJ, et al. (2003). "Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry.". Mol. Cell Proteomics 1 (12): 947-55. PMID 12543931.
- Langbein L, Rogers MA, Winter H, et al. (1999). "The catalog of human hair keratins. I. Expression of the nine type I members in the hair follicle.". J. Biol. Chem. 274 (28): 19874-84. PMID 10391933.
- Rogers MA, Winter H, Langbein L, et al. (1996). "Genomic characterization of the human type I cuticular hair keratin hHa2 and identification of an adjacent novel type I hair keratin gene hHa5.". J. Invest. Dermatol. 107 (4): 633-8. PMID 8823373.
- Rogers MA, Nischt R, Korge B, et al. (1995). "Sequence data and chromosomal localization of human type I and type II hair keratin genes.". Exp. Cell Res. 220 (2): 357-62. doi:. PMID 7556444.
- Heid HW, Moll I, Franke WW (1988). "Patterns of expression of trichocytic and epithelial cytokeratins in mammalian tissues. I. Human and bovine hair follicles.". Differentiation 37 (2): 137-57. PMID 2456239.

