KLF7

From Wikipedia, the free encyclopedia

Kruppel-like factor 7 (ubiquitous)

Identifiers

KLF7; UKLF

External IDs

OMIM: 604865 MGI: 1935151 HomoloGene: 2751

Gene ontology
Molecular Function:	• transcription factor activity • transcription coactivator activity • zinc ion binding • metal ion binding
Cellular Component:	• intracellular • nucleus
Biological Process:	• transcription • regulation of transcription from RNA polymerase II promoter

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_003709 (mRNA)
NP_003700 (protein)

XM_992457 (mRNA)
XP_997551 (protein)

Location

Chr 2: 207.65 - 207.74 Mb

Chr 1: 63.97 - 64.06 Mb

Pubmed search

[1]

[2]

Kruppel-like factor 7 (ubiquitous), also known as KLF7, is a human gene.^[1]

[edit] References

^ Entrez Gene: KLF7 Kruppel-like factor 7 (ubiquitous).

[edit] Further reading

Cho SY, Park PJ, Shin HJ, et al. (2007). "(-)-Catechin suppresses expression of Kruppel-like factor 7 and increases expression and secretion of adiponectin protein in 3T3-L1 cells.". Am. J. Physiol. Endocrinol. Metab. 292 (4): E1166-72. doi:10.1152/ajpendo.00436.2006. PMID 17164435.
Kawamura Y, Tanaka Y, Kawamori R, Maeda S (2006). "Overexpression of Kruppel-like factor 7 regulates adipocytokine gene expressions in human adipocytes and inhibits glucose-induced insulin secretion in pancreatic beta-cell line.". Mol. Endocrinol. 20 (4): 844-56. doi:10.1210/me.2005-0138. PMID 16339272.
Kanazawa A, Kawamura Y, Sekine A, et al. (2005). "Single nucleotide polymorphisms in the gene encoding Krüppel-like factor 7 are associated with type 2 diabetes.". Diabetologia 48 (7): 1315-22. doi:10.1007/s00125-005-1797-0. PMID 15937668.
Smaldone S, Laub F, Else C, et al. (2004). "Identification of MoKA, a novel F-box protein that modulates Krüppel-like transcription factor 7 activity.". Mol. Cell. Biol. 24 (3): 1058-69. PMID 14729953.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039.
Suzuki S, Chuang LF, Doi RH, Chuang RY (2004). "Identification of opioid-regulated genes in human lymphocytic cells by differential display: upregulation of Krüppel-like factor 7 by morphine.". Exp. Cell Res. 291 (2): 340-51. PMID 14644156.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Matsumoto N, Laub F, Aldabe R, et al. (1998). "Cloning the cDNA for a new human zinc finger protein defines a group of closely related Krüppel-like transcription factors.". J. Biol. Chem. 273 (43): 28229-37. PMID 9774444.