KIF1C

From Wikipedia, the free encyclopedia

Kinesin family member 1C

PDB rendering based on 2g1l.

Available structures: 2g1l

Identifiers

Symbol(s)

KIF1C; KIAA0706; LTXS1

External IDs

OMIM: 603060 MGI: 1098260 HomoloGene: 4821

Gene ontology
Molecular Function:	• nucleotide binding • microtubule motor activity • ATP binding
Cellular Component:	• endoplasmic reticulum • Golgi apparatus • cytoskeleton • microtubule • microtubule associated complex
Biological Process:	• retrograde vesicle-mediated transport, Golgi to ER • microtubule-based movement

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_006612 (mRNA)
NP_006603 (protein)

NM_153103 (mRNA)
NP_694743 (protein)

Location

Chr 17: 4.84 - 4.87 Mb

Chr 11: 70.52 - 70.55 Mb

Pubmed search

[1]

[2]

Kinesin family member 1C, also known as KIF1C, is a human gene.^[1]

[edit] References

^ Entrez Gene: KIF1C kinesin family member 1C.

[edit] Further reading

Dorner C, Ciossek T, Müller S, et al. (1998). "Characterization of KIF1C, a new kinesin-like protein involved in vesicle transport from the Golgi apparatus to the endoplasmic reticulum.". J. Biol. Chem. 273 (32): 20267-75. PMID 9685376.
Ishikawa K, Nagase T, Suyama M, et al. (1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.". DNA Res. 5 (3): 169-76. PMID 9734811.
Dorner C, Ullrich A, Häring HU, Lammers R (1999). "The kinesin-like motor protein KIF1C occurs in intact cells as a dimer and associates with proteins of the 14-3-3 family.". J. Biol. Chem. 274 (47): 33654-60. PMID 10559254.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173-8. doi:10.1038/nature04209. PMID 16189514.
Kopp P, Lammers R, Aepfelbacher M, et al. (2006). "The kinesin KIF1C and microtubule plus ends regulate podosome dynamics in macrophages.". Mol. Biol. Cell 17 (6): 2811-23. doi:10.1091/mbc.E05-11-1010. PMID 16554367.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization.". Nat. Biotechnol. 24 (10): 1285-92. doi:10.1038/nbt1240. PMID 16964243.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell 127 (3): 635-48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.