Kexin

From Wikipedia, the free encyclopedia

This article or section needs to be wikified to meet Wikipedia's quality standards. Please help improve this article with relevant internal links. (November 2007)

Kexin is a prohormone processing protease found in the budding yeast (Saccharomyces cerevisiae) that shares structural similarities with the bacterial protease subtilisin (1). It is encoded by the yeast gene KEX2 and usually referred to in the scientific community as Kex2p. The first mammalian homologue of this protein to be identified was furin.

[edit] References

(1) Rockwell, Nathan C.; Krysan, Damian J.; Komiyama, Tomoko; Fuller, Robert S. (2002) "Precursor processing by Kex2/furin proteases" Chem. Rev. 102: 4525-4548.