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| Kaposi's sarcoma-associated herpesvirus internal ribosome entry site (IRES) |
 |
| Type: |
Cis-reg; IRES; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
Published; PubMed |
| Avg length: |
248.0 nucleotides |
| Avg identity: |
99% |
|
This family represents the Kaposi's sarcoma-associated herpesvirus (KSHV) internal ribosome entry site (IRES) present in the vCyclin gene. The vCyclin and vFLIP coding sequences are present on a bicistronic transcript and it is thought the IRES may initiate translation of vFLIP from this bicistronic transcript.[1][2]
[edit] References
- ^ Bieleski, L; Talbot SJ (2001). "Kaposi's sarcoma-associated herpesvirus vCyclin open reading frame contains an internal ribosome entry site". J Virol 75: 1864–1869. doi:10.1128/JVI.75.4.1864-1869.2001. PMID 11160685.
- ^ Bieleski, L; Hindley C, Talbot SJ (2004). "A polypyrimidine tract facilitates the expression of Kaposi's sarcoma-associated herpesvirus vFLIP through an internal ribosome entry site". J Gen Virol 85: 615–620. doi:10.1099/vir.0.19733-0. PMID 14993645.
[edit] External links
