Kaempferol

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Kaempferol
Kaempferol
IUPAC name 3,5,7-trihydroxy-2-
(4-hydroxyphenyl)-4H-1-
benzopyran-4-one
Identifiers
CAS number [520-18-3]
Properties
Molecular formula C15H10O6
Molar mass 286.23 g/mol
Melting point

276-278 °C

Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

Kaempferol is a natural flavonoid that has been isolated from tea,[1] broccoli, Delphinium, Witch-hazel, grapefruit, and other plant sources. Kaempferol is a yellow crystalline solid with a melting point of 276-278 °C. It is slightly soluble in water but soluble in hot ethanol and diethyl ether.

Many glycosides of kaempferol, such as kaemferitrin and astragalin, have been isolated as natural products from plants. Kaempferol consumption in tea and broccoli has been associated with reduced risk of heart disease.[citation needed]

Kaempferol is what gives the flowers of Acacia decurrens and Acacia longifolia their color.[2] The compound has antidepressant properties.[3]

An 8-year study found that three flavonols (kaempferol, quercetin, and myricetin) reduced the risk of pancreatic cancer by 23 percent.[4]

[edit] References

  1. ^ Jun Seong Park, Ho Sik Rho, Duck Hee Kim, and Ih Seop Chang (2006). "Enzymatic Preparation of Kaempferol from Green Tea Seed and Its Antioxidant Activity". J. Agric. Food Chem. 54 (8): 2951–2956. doi:10.1021/jf052900a. 
  2. ^ Lycaeum -- Phytochemistry Intro
  3. ^ "ANTIDEPRESSANT EFFECT OF KAEMPFEROL, A CONSTITUENT OF SAFFRON (CROCUS SATIVUS) PETAL, IN MICE AND RATS" . Pharmacologyonline. 
  4. ^ Ute Nöthlings, Suzanne P. Murphy, Lynne R. Wilkens, Brian E. Henderson & Laurence N. Kolone. 2007. Flavonols and Pancreatic Cancer Risk. American Journal of Epidemiology 166(8): 924–931. doi:10.1093/aje/kwm172

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