Isoflavone 4'-O-methyltransferase

From Wikipedia, the free encyclopedia

In enzymology, an isoflavone 4'-O-methyltransferase (EC 2.1.1.46) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + an isoflavone S-adenosyl-L-homocysteine + a 4'-O-methylisoflavone

Thus, the two substrates of this enzyme are S-adenosyl methionine and isoflavone, whereas its two products are S-adenosylhomocysteine and 4'-O-methylisoflavone.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:isoflavone 4'-O-methyltransferase. Other names in common use include 4'-hydroxyisoflavone methyltransferase, isoflavone methyltransferase, and isoflavone O-methyltransferase. This enzyme participates in isoflavonoid biosynthesis.

[edit] References

• IUBMB entry for 2.1.1.46
• BRENDA references for 2.1.1.46 (Recommended.)
• PubMed references for 2.1.1.46
• PubMed Central references for 2.1.1.46
• Google Scholar references for 2.1.1.46
• Wengenmayer H, Ebel J, Grisebach H (1974). "Purification and properties of a S-adenosylmethionine: isoflavone 4'-O-methyltransferase from cell suspension cultures of Cicer arietinum L". Eur. J. Biochem. 50: 135–43. doi:10.1111/j.1432-1033.1974.tb03881.x. PMID 4452353. 

[edit] External links

The CAS registry number for this enzyme class is 55071-80-2.

• IUBMB entry for 2.1.1.46

• KEGG entry for 2.1.1.46

• BRENDA entry for 2.1.1.46

• NiceZyme view of 2.1.1.46

• EC2PDB: PDB structures for 2.1.1.46

• PRIAM entry for 2.1.1.46

• PUMA2 entry for 2.1.1.46

• IntEnz: Integrated Enzyme entry for 2.1.1.46

• MetaCyc entry for 2.1.1.46

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0030746: isoflavone 4'-O-methyltransferase

• AMIGO entry for GO code 0030746: isoflavone 4'-O-methyltransferase