Talk:Interferon beta-1a

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[edit] NPOV dispute

These drugs have some awful side-effects which make them undesirable to many relapsing-remitting MS sufferers who can otherwise tolerate their symptoms. For patient reports you might look here [1] and here [2]. Whig (talk · contribs)

While these drugs do have side effects, these effects diminsh in time. The alternative is to not use them, allow the disease to progress and possibly leave you a crippled, disease ravaged invalid. While not perfect, these medications are the best and only line of defense against a horrible illness. As someone that is currently on Avonex, I can say that after three years of therapy, the worst part of the treatment is the needle! The side effects have become a non-issue. A slight headache is all that I experience and this can be eliminated by simply taking Advil, Tylenol or Alieve prior to taking the injection.

Natalizumab is by far the most effective med. on the market for RR MS. But most neurologists consider it substantially more dangerous so it isn't prescribed nearly as often. Interferon is considered closer to over-the-counter medicine regarding its safty. —Preceding unsigned comment added by 18.87.1.114 (talk) 07:53, 8 April 2008 (UTC)

Interferon is hardly comparable to OTC drugs with respect to adverse events; flu-like myalgias, fatigue and general malaise which may actually worsen after 2 weeks use, injection site reactions + skin necrosis, lipoatrophy and an association with psychiatric sx, e.g. depression.

You make a good point about the pre-treatment prophylaxis with acetaminophen/antihistamine.

Natalizumab is actually much more tolerable; assuming no contraindications of allergies to it or any of its components or a history of PML it fares well. If you go past the first 7 days without signs of hepatotoxicity it can be expected to be tolerated quite well. —Preceding unsigned comment added by 134.153.184.17 (talk) 16:15, 12 April 2008 (UTC)

Inappropriate use of the NPOV tag. Just insert the info yourself! JFW | T@lk 06:55, 16 Jun 2005 (UTC)