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| Insulin-like growth factor II IRES |
 |
| Type: |
Cis-reg; IRES; |
| 2° structure: |
Published; PubMed |
| Seed alignment: |
Moxon SJ |
| Avg length: |
118.4 nucleotides |
| Avg identity: |
95% |
|
The insulin-like growth factor II (IGF-II) internal ribosome entry site IRES is found in the 5' UTR of IGF-II leader 2 mRNA. This RNA element allows cap-independent translation of the mRNA and it is thought that this family may facilitate a continuous IGF-II production in rapidly dividing cells during development.[1]
[edit] References
- ^ Pedersen, SK; Christiansen J, Hansen TO, Larsen MR, Nielsen FC (2002). "Human insulin-like growth factor II leader 2 mediates internal initiation of translation". Biochem J 363: 37–44. doi:10.1042/0264-6021:3630037. PMID 11903044.
[edit] External links
