Inositol 4-methyltransferase

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In enzymology, an inositol 4-methyltransferase (EC 2.1.1.129) is an enzyme that catalyzes the chemical reaction

S-adenosyl-L-methionine + myo-inositol $\rightleftharpoons$ S-adenosyl-L-homocysteine + 1D-4-O-methyl-myo-inositol

Thus, the two substrates of this enzyme are S-adenosyl methionine and myo-inositol, whereas its two products are S-adenosylhomocysteine and 1D-4-O-methyl-myo-inositol.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:1D-myo-inositol 4-methyltransferase. Other names in common use include myo-inositol 4-O-methyltransferase, S-adenosyl-L-methionine:myo-inositol 4-O-methyltransferase, and myo-inositol 6-O-methyltransferase.

[edit] References

IUBMB entry for 2.1.1.129
BRENDA references for 2.1.1.129 (Recommended.)
PubMed references for 2.1.1.129
PubMed Central references for 2.1.1.129
Google Scholar references for 2.1.1.129
Vernon DM, Bohnert HJ (1992). "A novel methyl transferase induced by osmotic stress in the facultative halophyte Mesembryanthemum crystallinum". EMBO. J. 11: 2077–85. PMID 1600940.
Wanek W and Richter A (1995). "Purification and characterization of myo-inositol 6-O-methyltransferase from Vigna umbellata Ohwi et Ohashi". Planta 197: 427–434.