IGSF1

From Wikipedia, the free encyclopedia

Immunoglobulin superfamily, member 1

Identifiers

IGSF1; IGCD1; IGDC1; INHBP; KIAA0364; MGC75490; PGSF2

External IDs

OMIM: 300137 MGI: 2147913 HomoloGene: 1195

Gene ontology
Molecular Function:	• receptor activity • protein binding • protein homodimerization activity • inhibin beta-A binding • inhibin beta-B binding
Cellular Component:	• plasma membrane • integral to plasma membrane
Biological Process:	• cell adhesion • signal transduction • regulation of transcription

RNA expression pattern

More reference expression data

Orthologs

Human

Mouse

Refseq

NM_001555 (mRNA)
NP_001546 (protein)

NM_177591 (mRNA)
NP_808259 (protein)

Location

Chr X: 130.24 - 130.36 Mb

Chr X: 46.03 - 46.04 Mb

Pubmed search

[1]

[2]

Immunoglobulin superfamily, member 1, also known as IGSF1, is a human gene.^[1]

Members of the immunoglobulin (Ig) superfamily (see MIM 147100), which includes IGSF1, have a variety of functions, but all appear to play a role in cell recognition and the regulation of cell behavior.[supplied by OMIM]^[1]

[edit] References

^ ^a ^b Entrez Gene: IGSF1 immunoglobulin superfamily, member 1.

[edit] Further reading

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298.
Nagase T, Ishikawa K, Nakajima D, et al. (1997). "Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.". DNA Res. 4 (2): 141–50. PMID 9205841.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149.
Mazzarella R, Pengue G, Jones J, et al. (1998). "Cloning and expression of an immunoglobulin superfamily gene (IGSF1) in Xq25.". Genomics 48 (2): 157–62. doi:10.1006/geno.1997.5156. PMID 9521868.
Frattini A, Faranda S, Redolfi E, et al. (1998). "Identification and genomic organization of a gene coding for a new member of the cell adhesion molecule family mapping to Xq25.". Gene 214 (1-2): 1–6. PMID 9729118.
Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863.
Chapman SC, Woodruff TK (2001). "Modulation of activin signal transduction by inhibin B and inhibin-binding protein (INhBP).". Mol. Endocrinol. 15 (4): 668–79. PMID 11266516.
Gui Y, Murphy LJ (2001). "Insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) binds to fibronectin (FN): demonstration of IGF-I/IGFBP-3/fn ternary complexes in human plasma.". J. Clin. Endocrinol. Metab. 86 (5): 2104–10. PMID 11344214.
Kushlinskii NE, Britvin TA, Polyakova GA, et al. (2002). "Soluble Fas antigen (sFAS) in the serum from patients with adrenal tumors.". Bull. Exp. Biol. Med. 132 (4): 990–2. PMID 11782802.
Tanaka S, Tatsumi K, Okubo K, et al. (2002). "Expression profile of active genes in the human pituitary gland.". J. Mol. Endocrinol. 28 (1): 33–44. PMID 11854097.
Aschkenazi S, Straszewski S, Verwer KM, et al. (2003). "Differential regulation and function of the Fas/Fas ligand system in human trophoblast cells.". Biol. Reprod. 66 (6): 1853–61. PMID 12021072.
Nat R, Radu E, Regalia T, Popescu LM (2002). "Apoptosis in human embryo development: 3. Fas-induced apoptosis in brain primary cultures.". J. Cell. Mol. Med. 5 (4): 417–28. PMID 12067476.
Fujita T, Maruyama M, Araya J, et al. (2002). "Hydrogen peroxide induces upregulation of Fas in human airway epithelial cells via the activation of PARP-p53 pathway.". Am. J. Respir. Cell Mol. Biol. 27 (5): 542–52. PMID 12397013.
Albertine KH, Soulier MF, Wang Z, et al. (2002). "Fas and fas ligand are up-regulated in pulmonary edema fluid and lung tissue of patients with acute lung injury and the acute respiratory distress syndrome.". Am. J. Pathol. 161 (5): 1783–96. PMID 12414525.
Nakayama M, Kikuno R, Ohara O (2003). "Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.". Genome Res. 12 (11): 1773–84. doi:10.1101/gr.406902. PMID 12421765.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Ivanov VN, Lopez Bergami P, Maulit G, et al. (2003). "FAP-1 association with Fas (Apo-1) inhibits Fas expression on the cell surface.". Mol. Cell. Biol. 23 (10): 3623–35. PMID 12724420.
Bilinska M, Frydecka I, Podemski R, Gruszka E (2003). "Fas expression on T cells and sFas in relapsing-remitting multiple sclerosis.". Acta Neurol. Scand. 107 (6): 387–93. PMID 12757469.
Strauss G, Knape I, Melzner I, Debatin KM (2003). "Constitutive caspase activation and impaired death-inducing signaling complex formation in CD95-resistant, long-term activated, antigen-specific T cells.". J. Immunol. 171 (3): 1172–82. PMID 12874203.
Marsik C, Halama T, Cardona F, et al. (2004). "Regulation of Fas (APO-1, CD95) and Fas ligand expression in leukocytes during systemic inflammation in humans.". Shock 20 (6): 493–6. doi:10.1097/01.shk.0000097248.97298.ea. PMID 14625471.