IFNA7

From Wikipedia, the free encyclopedia

Interferon, alpha 7

Identifiers

IFNA7; IFNA-J

External IDs

Gene ontology
Molecular Function:	• interferon-alpha/beta receptor binding
Cellular Component:	• extracellular region • extracellular space
Biological Process:	• defense response • cell-cell signaling • response to virus

Orthologs

Human

Mouse

Entrez

3444

n/a

Refseq

NM_021057 (mRNA)
NP_066401 (protein)

n/a (mRNA)
n/a (protein)

Pubmed search

[1]

n/a

Interferon, alpha 7, also known as IFNA7, is a human gene.^[1]

[edit] References

^ Entrez Gene: IFNA7 interferon, alpha 7.

[edit] Further reading

Conti L, Fantuzzi L, Del Cornò M, et al. (2005). "Immunomodulatory effects of the HIV-1 gp120 protein on antigen presenting cells: implications for AIDS pathogenesis.". Immunobiology 209 (1-2): 99-115. PMID 15481145.
Capobianchi MR, Ankel H, Ameglio F, et al. (1992). "Recombinant glycoprotein 120 of human immunodeficiency virus is a potent interferon inducer.". AIDS Res. Hum. Retroviruses 8 (5): 575-9. PMID 1381203.
Olopade OI, Bohlander SK, Pomykala H, et al. (1992). "Mapping of the shortest region of overlap of deletions of the short arm of chromosome 9 associated with human neoplasia.". Genomics 14 (2): 437-43. PMID 1385305.
Tyring SK, Cauda R, Tumbarello M, et al. (1991). "Synthetic peptides corresponding to sequences in HIV envelope gp41 and gp120 enhance in vitro production of interleukin-1 and tumor necrosis factor but depress production of interferon-alpha, interferon-gamma and interleukin-2.". Viral Immunol. 4 (1): 33-42. PMID 1905933.
Stine KC, Bolognesi D, Weinhold KJ (1989). "Cytokine augmentation of human immunodeficiency virus type 1 (HIV-1) gp120-specific cellular cytotoxicity.". Journal of biological response modifiers 8 (5): 501-10. PMID 2552026.
Cohen S, Velan B, Grosfeld H, et al. (1985). "Cloning, expression and biological activity of a new variant of human interferon alpha identified in virus induced lymphoblastoid cells.". Dev. Biol. Stand. 60: 111-22. PMID 2995168.
Henco K, Brosius J, Fujisawa A, et al. (1985). "Structural relationship of human interferon alpha genes and pseudogenes.". J. Mol. Biol. 185 (2): 227-60. PMID 4057246.
Ullrich A, Gray A, Goeddel DV, Dull TJ (1982). "Nucleotide sequence of a portion of human chromosome 9 containing a leukocyte interferon gene cluster.". J. Mol. Biol. 156 (3): 467-86. PMID 6181262.
Ameglio F, Capobianchi MR, Castilletti C, et al. (1994). "Recombinant gp120 induces IL-10 in resting peripheral blood mononuclear cells; correlation with the induction of other cytokines.". Clin. Exp. Immunol. 95 (3): 455-8. PMID 7511078.
Ankel H, Capobianchi MR, Castilletti C, Dianzani F (1994). "Interferon induction by HIV glycoprotein 120: role of the V3 loop.". Virology 205 (1): 34-43. doi:10.1006/viro.1994.1617. PMID 7526537.
Nair MP, Chadha KC, Stadler I, et al. (1995). "Differential effects of human immunodeficiency virus type 1 envelope protein gp120 on interferon production by mononuclear cells from adults and neonates.". Clin. Diagn. Lab. Immunol. 2 (4): 434-8. PMID 7583919.
Borghi P, Fantuzzi L, Varano B, et al. (1995). "Induction of interleukin-10 by human immunodeficiency virus type 1 and its gp120 protein in human monocytes/macrophages.". J. Virol. 69 (2): 1284-7. PMID 7815507.
Capobianchi MR, Ameglio F, Cordiali Fei P, et al. (1994). "Coordinate induction of interferon alpha and gamma by recombinant HIV-1 glycoprotein 120.". AIDS Res. Hum. Retroviruses 9 (10): 957-62. PMID 7904170.
Chen YH, Böck G, Vornhagen R, et al. (1994). "HIV-1 gp41 enhances major histocompatibility complex class I and ICAM-1 expression on H9 and U937 cells.". Int. Arch. Allergy Immunol. 104 (3): 227-31. PMID 7913356.
Francis ML, Meltzer MS (1993). "Induction of IFN-alpha by HIV-1 in monocyte-enriched PBMC requires gp120-CD4 interaction but not virus replication.". J. Immunol. 151 (4): 2208-16. PMID 8345204.
Shirazi Y, Pitha PM (1993). "Interferon alpha-mediated inhibition of human immunodeficiency virus type 1 provirus synthesis in T-cells.". Virology 193 (1): 303-12. doi:10.1006/viro.1993.1126. PMID 8438572.
Ankel H, Capobianchi MR, Frezza F, et al. (1996). "Interferon induction by HIV-1-infected cells: a possible role of sulfatides or related glycolipids.". Virology 221 (1): 113-9. doi:10.1006/viro.1996.0357. PMID 8661419.
Tiefenbrun N, Melamed D, Levy N, et al. (1996). "Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.". Mol. Cell. Biol. 16 (7): 3934-44. PMID 8668211.
Schols D, De Clercq E (1996). "Human immunodeficiency virus type 1 gp120 induces anergy in human peripheral blood lymphocytes by inducing interleukin-10 production.". J. Virol. 70 (8): 4953-60. PMID 8764000.
Hussain M, Gill DS, Liao MJ (1997). "Identification of interferon-alpha 7, -alpha 14, and -alpha 21 variants in the genome of a large human population.". J. Interferon Cytokine Res. 16 (10): 853-9. PMID 8910771.