Hydroxypyruvate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, a hydroxypyruvate decarboxylase (EC 4.1.1.40) is an enzyme that catalyzes the chemical reaction

hydroxypyruvate glycolaldehyde + CO₂

Hence, this enzyme has one substrate, hydroxypyruvate, and two products, glycolaldehyde and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is hydroxypyruvate carboxy-lyase (glycolaldehyde-forming). This enzyme is also called hydroxypyruvate carboxy-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.

[edit] References

• IUBMB entry for 4.1.1.40
• BRENDA references for 4.1.1.40 (Recommended.)
• PubMed references for 4.1.1.40
• PubMed Central references for 4.1.1.40
• Google Scholar references for 4.1.1.40
• HEDRICK JL, SALLACH HJ (1964). "THE NONOXIDATIVE DECARBOXYLATION OF HYDROXYPYRUVATE IN MAMMALIAN SYSTEMS". Arch. Biochem. Biophys. 105: 261–9. doi:10.1016/0003-9861(64)90007-4. PMID 14186730. 

[edit] External links

The CAS registry number for this enzyme class is 37289-43-3.

• IUBMB entry for 4.1.1.40

• KEGG entry for 4.1.1.40

• BRENDA entry for 4.1.1.40

• NiceZyme view of 4.1.1.40

• EC2PDB: PDB structures for 4.1.1.40

• PRIAM entry for 4.1.1.40

• PUMA2 entry for 4.1.1.40

• IntEnz: Integrated Enzyme entry for 4.1.1.40

• MetaCyc entry for 4.1.1.40

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047997: hydroxypyruvate decarboxylase

• AMIGO entry for GO code 0047997: hydroxypyruvate decarboxylase