Hydroxymandelonitrile glucosyltransferase

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In enzymology, a hydroxymandelonitrile glucosyltransferase (EC 2.4.1.178) is an enzyme that catalyzes the chemical reaction

UDP-glucose + 4-hydroxymandelonitrile $\rightleftharpoons$ UDP + taxiphyllin

Thus, the two substrates of this enzyme are UDP-glucose and 4-hydroxymandelonitrile, whereas its two products are UDP and taxiphyllin.

This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:4-hydroxymandelonitrile glucosyltransferase. Other names in common use include cyanohydrin glucosyltransferase, and uridine diphosphoglucose-cyanohydrin glucosyltransferase. This enzyme participates in tyrosine metabolism.

[edit] References

IUBMB entry for 2.4.1.178
BRENDA references for 2.4.1.178 (Recommended.)
PubMed references for 2.4.1.178
PubMed Central references for 2.4.1.178
Google Scholar references for 2.4.1.178
Hosel W, Schiel O (1984). "Biosynthesis of cyanogenic glucosides: in vitro analysis of the glucosylation step". Arch. Biochem. Biophys. 229: 177–86. PMID 6230992.
Poulton JE and Shin S-I (1983). "Prunasin biosynthesis by cell-free-extracts from black cherry (Prunus serotina Ehrh) fruits and leaves". Z. Naturforsch. C: Biosci. 38: 369–374.