Hydroxyglutamate decarboxylase

From Wikipedia, the free encyclopedia

In enzymology, a hydroxyglutamate decarboxylase (EC 4.1.1.16) is an enzyme that catalyzes the chemical reaction

3-hydroxy-L-glutamate 4-amino-3-hydroxybutanoate + CO₂

Hence, this enzyme has one substrate, 3-hydroxy-L-glutamate, and two products, 4-amino-3-hydroxybutanoate and CO₂.

This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is 3-hydroxy-L-glutamate 1-carboxy-lyase (4-amino-3-hydroxybutanoate-forming). This enzyme is also called 3-hydroxy-L-glutamate 1-carboxy-lyase. It employs one cofactor, pyridoxal phosphate.

[edit] References

• IUBMB entry for 4.1.1.16
• BRENDA references for 4.1.1.16 (Recommended.)
• PubMed references for 4.1.1.16
• PubMed Central references for 4.1.1.16
• Google Scholar references for 4.1.1.16
• Umbreit WW and Heneage P (1953). "beta-Hydroxyglutamic acid decarboxylase". J. Biol. Chem. 201: 15–20. 

[edit] External links

The CAS registry number for this enzyme class is 9024-59-3.

• IUBMB entry for 4.1.1.16

• KEGG entry for 4.1.1.16

• BRENDA entry for 4.1.1.16

• NiceZyme view of 4.1.1.16

• EC2PDB: PDB structures for 4.1.1.16

• PRIAM entry for 4.1.1.16

• PUMA2 entry for 4.1.1.16

• IntEnz: Integrated Enzyme entry for 4.1.1.16

• MetaCyc entry for 4.1.1.16

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047990: hydroxyglutamate decarboxylase

• AMIGO entry for GO code 0047990: hydroxyglutamate decarboxylase