Human rhinovirus internal cis-acting regulatory element (CRE)

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Human rhinovirus internal cis-acting regulatory element (CRE)
Template:Abbreviation
Type: Cis-reg;
2° structure: Published; PubMed
Seed alignment: PubMed
Avg length: 85.5 nucleotides
Avg identity: 72%

Human rhinovirus internal cis-acting regulatory element (CRE) is a CRE from the human rhinoviruses. The CRE is located within the genome segment encoding the capsid proteins so is found in a protein coding region. The element is essential for efficient viral replication and it has been suggested that the CRE is required for initiation of minus-strand RNA synthesis [1].

[edit] References

  1. ^ McKnight, KL; Lemon SM (1998). "The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication". RNA 4: 1569–1584. doi:10.1017/S1355838298981006. PMID 9848654. 

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