Hsp90 cis-regulatory element

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Hsp90 cis-regulatory element
Template:Abbreviation
Type: Cis-reg; thermoregulator;
2° structure: Published; PubMed
Seed alignment: PubMed
Avg length: 152.0 nucleotides
Avg identity: 98%

The Hsp90 cis regulatory element is an RNA element found in the 5' UTR of the Drosophila hsp90 mRNA that is required for increased translational efficiency during the heat shock response. The hsp90 gene product is involved in the Drosophila heat shock response and translation of the hsp90 mRNA is very inefficient under normal growth temperatures. When heat shock occurs translation becomes more efficient.[1]

[edit] References

  1. ^ Ahmed, R; Duncan RF (2004). "Translational regulation of Hsp90 mRNA. AUG-proximal 5'-untranslated region elements essential for preferential heat shock translation". J Biol Chem 279: 49919–49930. doi:10.1074/jbc.M404681200. PMID 15347681. 

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