HSPBP1

From Wikipedia, the free encyclopedia


Hsp70-interacting protein
PDB rendering based on 1xqr.
Available structures: 1xqr, 1xqs
Identifiers
Symbol(s) HSPBP1;
External IDs MGI: 1913495 HomoloGene: 40827
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 23640 66245
Ensembl ENSG00000133265 ENSMUSG00000063802
Uniprot Q9NZL4 Q99P31
Refseq XM_001128038 (mRNA)
XP_001128038 (protein)		 NM_024172 (mRNA)
NP_077134 (protein)
Location Chr 19: 60.47 - 60.48 Mb Chr 7: 4.26 - 4.29 Mb
Pubmed search [1] [2]

Hsp70-interacting protein, also known as HSPBP1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: HSPBP1 hsp70-interacting protein.

[edit] Further reading

  • Zou J, Guo Y, Guettouche T, et al. (1998). "Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1.". Cell 94 (4): 471–80. PMID 9727490. 
  • Raynes DA, Guerriero V (1999). "Inhibition of Hsp70 ATPase activity and protein renaturation by a novel Hsp70-binding protein.". J. Biol. Chem. 273 (49): 32883–8. PMID 9830037. 
  • Raynes DA, Guerriero V (2000). "Isolation and characterization of isoforms of HspBP1, inhibitors of Hsp70.". Biochim. Biophys. Acta 1490 (1-2): 203–7. PMID 10786638. 
  • Kabani M, McLellan C, Raynes DA, et al. (2002). "HspBP1, a homologue of the yeast Fes1 and Sls1 proteins, is an Hsc70 nucleotide exchange factor.". FEBS Lett. 531 (2): 339–42. PMID 12417338. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • McLellan CA, Raynes DA, Guerriero V (2003). "HspBP1, an Hsp70 cochaperone, has two structural domains and is capable of altering the conformation of the Hsp70 ATPase domain.". J. Biol. Chem. 278 (21): 19017–22. doi:10.1074/jbc.M301109200. PMID 12651857. 
  • Oh WK, Song J (2004). "Cooperative interaction of Hsp40 and TPR1 with Hsp70 reverses Hsp70-HspBp1 complex formation.". Mol. Cells 16 (1): 84–91. PMID 14503850. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039. 
  • Lu QF, Bai M, Zhang HJ, et al. (2004). "[Co-detection of P21, P53 and HSP70 and their possible role in diagnosis of polycyclic aromatic hydrocarbons (PAHs)-related lung cancer]". Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 21 (5): 359–61. PMID 14761400. 
  • Alberti S, Böhse K, Arndt V, et al. (2005). "The cochaperone HspBP1 inhibits the CHIP ubiquitin ligase and stimulates the maturation of the cystic fibrosis transmembrane conductance regulator.". Mol. Biol. Cell 15 (9): 4003–10. doi:10.1091/mbc.E04-04-0293. PMID 15215316. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Shomura Y, Dragovic Z, Chang HC, et al. (2005). "Regulation of Hsp70 function by HspBP1: structural analysis reveals an alternate mechanism for Hsp70 nucleotide exchange.". Mol. Cell 17 (3): 367–79. doi:10.1016/j.molcel.2004.12.023. PMID 15694338. 
  • Stelzl U, Worm U, Lalowski M, et al. (2005). "A human protein-protein interaction network: a resource for annotating the proteome.". Cell 122 (6): 957–68. doi:10.1016/j.cell.2005.08.029. PMID 16169070. 
  • Dai Q, Qian SB, Li HH, et al. (2006). "Regulation of the cytoplasmic quality control protein degradation pathway by BAG2.". J. Biol. Chem. 280 (46): 38673–81. doi:10.1074/jbc.M507986200. PMID 16169850. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743. 
  • Gottwald E, Herschbach M, Lahni B, et al. (2006). "Expression of the cochaperone HspBP1 is not coordinately regulated with Hsp70 expression.". Cell Biol. Int. 30 (6): 553–8. doi:10.1016/j.cellbi.2006.03.005. PMID 16677834. 
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
  • Bivik C, Rosdahl I, Ollinger K (2007). "Hsp70 protects against UVB induced apoptosis by preventing release of cathepsins and cytochrome c in human melanocytes.". Carcinogenesis 28 (3): 537–44. doi:10.1093/carcin/bgl152. PMID 16950797. 
  • Swayne LA, Braun JE (2007). "Aggregate-centered redistribution of proteins by mutant huntingtin.". Biochem. Biophys. Res. Commun. 354 (1): 39–44. doi:10.1016/j.bbrc.2006.12.129. PMID 17208201. 
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