HSPA4

From Wikipedia, the free encyclopedia


Heat shock 70kDa protein 4
Identifiers
Symbol(s) HSPA4; APG-2; HS24/P52; MGC131852; RY; hsp70; hsp70RY
External IDs OMIM: 601113 MGI: 1342292 HomoloGene: 1624
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 3308 15525
Ensembl ENSG00000170606 ENSMUSG00000020361
Uniprot P34932 Q571M2
Refseq NM_002154 (mRNA)
NP_002145 (protein)		 NM_008300 (mRNA)
NP_032326 (protein)
Location Chr 5: 132.42 - 132.47 Mb Chr 11: 53.1 - 53.14 Mb
Pubmed search [1] [2]

Heat shock 70kDa protein 4, also known as HSPA4, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: HSPA4 heat shock 70kDa protein 4.

[edit] Further reading

  • Abravaya K, Myers MP, Murphy SP, Morimoto RI (1992). "The human heat shock protein hsp70 interacts with HSF, the transcription factor that regulates heat shock gene expression.". Genes Dev. 6 (7): 1153–64. PMID 1628823. 
  • Liao J, Lowthert LA, Ghori N, Omary MB (1995). "The 70-kDa heat shock proteins associate with glandular intermediate filaments in an ATP-dependent manner.". J. Biol. Chem. 270 (2): 915–22. PMID 7529764. 
  • Furlini G, Vignoli M, Re MC, et al. (1994). "Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.". J. Gen. Virol. 75 ( Pt 1): 193–9. PMID 7906708. 
  • Fathallah DM, Cherif D, Dellagi K, Arnaout MA (1993). "Molecular cloning of a novel human hsp70 from a B cell line and its assignment to chromosome 5.". J. Immunol. 151 (2): 810–3. PMID 8335910. 
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. PMID 8889548. 
  • Schulte AM, Fischer S, Sachse GE, et al. (1997). "Identification and characterization of a novel hsc70-like gene in the human lung tumor cell line HS24.". DNA Cell Biol. 16 (3): 257–68. PMID 9115634. 
  • Kaneko Y, Kimura T, Kishishita M, et al. (1997). "Cloning of apg-2 encoding a novel member of heat shock protein 110 family.". Gene 189 (1): 19–24. PMID 9161406. 
  • Bruner KL, Derfoul A, Robertson NM, et al. (1998). "The unliganded mineralocorticoid receptor is associated with heat shock proteins 70 and 90 and the immunophilin FKBP-52.". Receptors & signal transduction 7 (2): 85–98. PMID 9392437. 
  • Satyal SH, Chen D, Fox SG, et al. (1998). "Negative regulation of the heat shock transcriptional response by HSBP1.". Genes Dev. 12 (13): 1962–74. PMID 9649501. 
  • Naylor DJ, Stines AP, Hoogenraad NJ, Høj PB (1998). "Evidence for the existence of distinct mammalian cytosolic, microsomal, and two mitochondrial GrpE-like proteins, the Co-chaperones of specific Hsp70 members.". J. Biol. Chem. 273 (33): 21169–77. PMID 9694873. 
  • Melville MW, Tan SL, Wambach M, et al. (1999). "The cellular inhibitor of the PKR protein kinase, P58(IPK), is an influenza virus-activated co-chaperone that modulates heat shock protein 70 activity.". J. Biol. Chem. 274 (6): 3797–803. PMID 9920933. 
  • Ballinger CA, Connell P, Wu Y, et al. (1999). "Identification of CHIP, a novel tetratricopeptide repeat-containing protein that interacts with heat shock proteins and negatively regulates chaperone functions.". Mol. Cell. Biol. 19 (6): 4535–45. PMID 10330192. 
  • Liu H, Vuyyuru VB, Pham CD, et al. (1999). "Evidence of an interaction between Mos and Hsp70: a role of the Mos residue serine 3 in mediating Hsp70 association.". Oncogene 18 (23): 3461–70. doi:10.1038/sj.onc.1202699. PMID 10376524. 
  • Nonoguchi K, Itoh K, Xue JH, et al. (1999). "Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes.". Gene 237 (1): 21–8. PMID 10524232. 
  • O'Keeffe B, Fong Y, Chen D, et al. (2000). "Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription.". J. Biol. Chem. 275 (1): 279–87. PMID 10617616. 
  • Agostini I, Popov S, Li J, et al. (2000). "Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.". Exp. Cell Res. 259 (2): 398–403. doi:10.1006/excr.2000.4992. PMID 10964507. 
  • Kim M, Jiang LH, Wilson HL, et al. (2002). "Proteomic and functional evidence for a P2X7 receptor signalling complex.". EMBO J. 20 (22): 6347–58. doi:10.1093/emboj/20.22.6347. PMID 11707406. 
  • Johnson CA, White DA, Lavender JS, et al. (2002). "Human class I histone deacetylase complexes show enhanced catalytic activity in the presence of ATP and co-immunoprecipitate with the ATP-dependent chaperone protein Hsp70.". J. Biol. Chem. 277 (11): 9590–7. doi:10.1074/jbc.M107942200. PMID 11777905. 
  • Gurer C, Cimarelli A, Luban J (2002). "Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.". J. Virol. 76 (9): 4666–70. PMID 11932435. 
  • Freeman BC, Yamamoto KR (2002). "Disassembly of transcriptional regulatory complexes by molecular chaperones.". Science 296 (5576): 2232–5. doi:10.1126/science.1073051. PMID 12077419. 
 This article on a gene on chromosome 5 is a stub. You can help Wikipedia by expanding it.