Hot 100 number-one hits of 1995 (USA)
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This is a list of the U.S. Billboard magazine Hot 100 number-ones of 1995.
| Issue Date | Song | Artist |
| January 7 | "On Bended Knee" | Boyz II Men |
| January 14 | "On Bended Knee" | Boyz II Men |
| January 21 | "On Bended Knee" | Boyz II Men |
| January 28 | "Creep" | TLC |
| February 4 | "Creep" | TLC |
| February 11 | "Creep" | TLC |
| February 18 | "Creep" | TLC |
| February 25 | "Take a Bow" | Madonna |
| March 4 | "Take a Bow" | Madonna |
| March 11 | "Take a Bow" | Madonna |
| March 18 | "Take a Bow" | Madonna |
| March 25 | "Take a Bow" | Madonna |
| April 1 | "Take a Bow" | Madonna |
| April 8 | "Take a Bow" | Madonna |
| April 15 | "This Is How We Do It" | Montell Jordan |
| April 22 | "This Is How We Do It" | Montell Jordan |
| April 29 | "This Is How We Do It" | Montell Jordan |
| May 6 | "This Is How We Do It" | Montell Jordan |
| May 13 | "This Is How We Do It" | Montell Jordan |
| May 20 | "This Is How We Do It" | Montell Jordan |
| May 27 | "This Is How We Do It" | Montell Jordan |
| June 3 | "Have You Ever Really Loved a Woman?" | Bryan Adams |
| June 10 | "Have You Ever Really Loved a Woman?" | Bryan Adams |
| June 17 | "Have You Ever Really Loved a Woman?" | Bryan Adams |
| June 24 | "Have You Ever Really Loved a Woman?" | Bryan Adams |
| July 1 | "Have You Ever Really Loved a Woman?" | Bryan Adams |
| July 8 | "Waterfalls" | TLC |
| July 15 | "Waterfalls" | TLC |
| July 22 | "Waterfalls" | TLC |
| July 29 | "Waterfalls" | TLC |
| August 5 | "Waterfalls" | TLC |
| August 12 | "Waterfalls" | TLC |
| August 19 | "Waterfalls" | TLC |
| August 26 | "Kiss from a Rose" | Seal |
| September 2 | "You Are Not Alone" | Michael Jackson |
| September 9 | "Gangsta's Paradise" | Coolio featuring L.V. |
| September 16 | "Gangsta's Paradise" | Coolio featuring L.V. |
| September 23 | "Gangsta's Paradise" | Coolio featuring L.V. |
| September 30 | "Fantasy" | Mariah Carey |
| October 7 | "Fantasy" | Mariah Carey |
| October 14 | "Fantasy" | Mariah Carey |
| October 21 | "Fantasy" | Mariah Carey |
| October 28 | "Fantasy" | Mariah Carey |
| November 4 | "Fantasy" | Mariah Carey |
| November 11 | "Fantasy" | Mariah Carey |
| November 18 | "Fantasy" | Mariah Carey |
| November 25 | "Exhale (Shoop Shoop)" | Whitney Houston |
| December 2 | "One Sweet Day" | Mariah Carey and Boyz II Men |
| December 9 | "One Sweet Day" | Mariah Carey and Boyz II Men |
| December 16 | "One Sweet Day" | Mariah Carey and Boyz II Men |
| December 23 | "One Sweet Day" | Mariah Carey and Boyz II Men |
| December 30 | "One Sweet Day" | Mariah Carey and Boyz II Men |
