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| HIV gag stem loop 3 (GSL3) |
 |
| Type: |
Cis-reg; |
| 2° structure: |
Predicted; PFOLD |
| Seed alignment: |
PubMed |
| Avg length: |
81.1 nucleotides |
| Avg identity: |
87% |
|
HIV gag stem loop 3 (GSL3) is an RNA element that is known to direct specific packaging of HIV-1 genomic RNA. Deletion of GSL3 leads to decreases in both viral RNA packaging and dimerisation.[1] [2]
[edit] References
- ^ Damgaard, CK; Andersen ES, Knudsen B, Gorodkin J, Kjems J (2004). "RNA interactions in the 5' region of the HIV-1 genome". J Mol Biol 336: 369–379. doi:10.1016/j.jmb.2003.12.010. PMID 14757051.
- ^ Rong, L; Russell RS, Hu J, Laughrea M, Wainberg MA, Liang C (2003). "Deletion of stem-loop 3 is compensated by second-site mutations within the Gag protein of human immunodeficiency virus type 1". Virology 314: 221–228. doi:10.1016/S0042-6822(03)00405-7. PMID 14517075.
[edit] External links
