Hippurate hydrolase

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In enzymology, a hippurate hydrolase (EC 3.5.1.32) is an enzyme that catalyzes the chemical reaction

hippurate + H₂O $\rightleftharpoons$ benzoate + glycine

Thus, the two substrates of this enzyme are hippurate and H₂O, whereas its two products are benzoate and glycine.

This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is N-benzoylamino-acid amidohydrolase. This enzyme participates in phenylalanine metabolism.

[edit] References

IUBMB entry for 3.5.1.32
BRENDA references for 3.5.1.32 (Recommended.)
PubMed references for 3.5.1.32
PubMed Central references for 3.5.1.32
Google Scholar references for 3.5.1.32
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Tsoi E, Akmal S, Geerts L, Jeffery B, Nicolaides KH (2006). "Sonographic measurement of cervical length and fetal fibronectin testing in threatened preterm labor". Ultrasound. Obstet. Gynecol. 27: 368–72. doi:10.1002/uog.2723. PMID 16526097.
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