Hexaprenyldihydroxybenzoate methyltransferase
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In enzymology, a hexaprenyldihydroxybenzoate methyltransferase (EC 2.1.1.114) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate
S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate
Thus, the two substrates of this enzyme are S-adenosyl methionine and 3-hexaprenyl-4,5-dihydroxybenzoate, whereas its two products are S-adenosylhomocysteine and 3-hexaprenyl-4-hydroxy-5-methoxybenzoate.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:3-hexaprenyl-4,5-dihydroxylate O-methyltransferase. Other names in common use include 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase, and dihydroxyhexaprenylbenzoate methyltransferase. This enzyme participates in ubiquinone biosynthesis.
[edit] References
- IUBMB entry for 2.1.1.114
- BRENDA references for 2.1.1.114 (Recommended.)
- PubMed references for 2.1.1.114
- PubMed Central references for 2.1.1.114
- Google Scholar references for 2.1.1.114
- Clarke CF, Williams W, Teruya JH (1991). "Ubiquinone biosynthesis in Saccharomyces cerevisiae. Isolation and sequence of COQ3, the 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase gene". J. Biol. Chem. 266: 16636–44. PMID 1885593.
[edit] External links
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- The CAS registry number for this enzyme class is 139569-30-5.
[edit] Gene Ontology (GO) codes
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