HERV-FRD

From Wikipedia, the free encyclopedia


HERV-FRD provirus ancestral Env polyprotein
PDB rendering based on 1y4m.
Available structures: 1y4m
Identifiers
Symbol(s) HERV-FRD; FLJ41944; FLJ90611; GLLL6191; MGC87585; UNQ6191
External IDs OMIM: 610524 MGI3045308 HomoloGene86779
Orthologs
Human Mouse
Entrez 405754 239167
Ensembl n/a ENSMUSG00000047977
Refseq NM_207582 (mRNA)
NP_997465 (protein)
NM_173420 (mRNA)
NP_775596 (protein)
Location n/a Chr 14: 68.24 - 68.25 Mb
Pubmed search [1] [2]

HERV-FRD provirus ancestral Env polyprotein, also known as HERV-FRD, is a human gene.[1]


[edit] References

[edit] Further reading

  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899-903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • de Parseval N, Lazar V, Casella JF, et al. (2003). "Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.". J. Virol. 77 (19): 10414-22. PMID 12970426. 
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265-70. doi:10.1101/gr.1293003. PMID 12975309. 
  • Blaise S, de Parseval N, Bénit L, Heidmann T (2004). "Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.". Proc. Natl. Acad. Sci. U.S.A. 100 (22): 13013-8. doi:10.1073/pnas.2132646100. PMID 14557543. 
  • Mungall AJ, Palmer SA, Sims SK, et al. (2003). "The DNA sequence and analysis of human chromosome 6.". Nature 425 (6960): 805-11. doi:10.1038/nature02055. PMID 14574404. 
  • Blaise S, Ruggieri A, Dewannieux M, et al. (2004). "Identification of an envelope protein from the FRD family of human endogenous retroviruses (HERV-FRD) conferring infectivity and functional conservation among simians.". J. Virol. 78 (2): 1050-4. PMID 14694139. 
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40-5. doi:10.1038/ng1285. PMID 14702039. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121-7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Renard M, Varela PF, Letzelter C, et al. (2005). "Crystal structure of a pivotal domain of human syncytin-2, a 40 million years old endogenous retrovirus fusogenic envelope gene captured by primates.". J. Mol. Biol. 352 (5): 1029-34. doi:10.1016/j.jmb.2005.07.058. PMID 16140326. 
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117-26. doi:10.1093/dnares/12.2.117. PMID 16303743. 
  • Malassiné A, Blaise S, Handschuh K, et al. (2007). "Expression of the fusogenic HERV-FRD Env glycoprotein (syncytin 2) in human placenta is restricted to villous cytotrophoblastic cells.". Placenta 28 (2-3): 185-91. doi:10.1016/j.placenta.2006.03.001. PMID 16714059.