HAVCR1

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Hepatitis A virus cellular receptor 1
Identifiers
Symbol(s) HAVCR1; TIM1; HAVCR; HAVCR-1; KIM-1; KIM1; TIM-1; TIMD1
External IDs OMIM: 606518 MGI: 2159680 HomoloGene: 77133
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 26762 171283
Ensembl ENSG00000113249 ENSMUSG00000040405
Uniprot Q96D42 Q5QNS5
Refseq NM_012206 (mRNA)
NP_036338 (protein)		 NM_134248 (mRNA)
NP_599009 (protein)
Location Chr 5: 156.39 - 156.42 Mb Chr 11: 46.58 - 46.62 Mb
Pubmed search [1] [2]

Hepatitis A virus cellular receptor 1, also known as HAVCR1, is a human gene.[1]


[edit] References

  1. ^ Entrez Gene: HAVCR1 hepatitis A virus cellular receptor 1.

[edit] Further reading

  • Kumanogoh A, Kikutani H (2004). "Immune semaphorins: a new area of semaphorin research.". J. Cell. Sci. 116 (Pt 17): 3463–70. doi:10.1242/jcs.00674. PMID 12893810. 
  • McIntire JJ, Umetsu DT, DeKruyff RH (2004). "TIM-1, a novel allergy and asthma susceptibility gene.". Springer Semin. Immunopathol. 25 (3-4): 335–48. doi:10.1007/s00281-003-0141-3. PMID 15007635. 
  • Thompson P, Lu J, Kaplan GG (1998). "The Cys-rich region of hepatitis A virus cellular receptor 1 is required for binding of hepatitis A virus and protective monoclonal antibody 190/4.". J. Virol. 72 (5): 3751–61. PMID 9557657. 
  • Feigelstock D, Thompson P, Mattoo P, et al. (1998). "The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor.". J. Virol. 72 (8): 6621–8. PMID 9658108. 
  • McIntire JJ, Umetsu SE, Akbari O, et al. (2001). "Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family.". Nat. Immunol. 2 (12): 1109–16. doi:10.1038/ni739. PMID 11725301. 
  • Bailly V, Zhang Z, Meier W, et al. (2002). "Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration.". J. Biol. Chem. 277 (42): 39739–48. doi:10.1074/jbc.M200562200. PMID 12138159. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Noguchi E, Nakayama J, Kamioka M, et al. (2003). "Insertion/deletion coding polymorphisms in hHAVcr-1 are not associated with atopic asthma in the Japanese population.". Genes Immun. 4 (2): 170–3. doi:10.1038/sj.gene.6363935. PMID 12618867. 
  • McIntire JJ, Umetsu SE, Macaubas C, et al. (2003). "Immunology: hepatitis A virus link to atopic disease.". Nature 425 (6958): 576. doi:10.1038/425576a. PMID 14534576. 
  • Chae SC, Song JH, Heo JC, et al. (2004). "Molecular variations in the promoter and coding regions of human Tim-1 gene and their association in Koreans with asthma.". Hum. Immunol. 64 (12): 1177–82. PMID 14630400. 
  • Chae SC, Song JH, Lee YC, et al. (2004). "The association of the exon 4 variations of Tim-1 gene with allergic diseases in a Korean population.". Biochem. Biophys. Res. Commun. 312 (2): 346–50. PMID 14637143. 
  • Vilà MR, Kaplan GG, Feigelstock D, et al. (2004). "Hepatitis A virus receptor blocks cell differentiation and is overexpressed in clear cell renal cell carcinoma.". Kidney Int. 65 (5): 1761–73. doi:10.1111/j.1523-1755.2004.00601.x. PMID 15086915. 
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560. 
  • Mesri M, Smithson G, Ghatpande A, et al. (2006). "Inhibition of in vitro and in vivo T cell responses by recombinant human Tim-1 extracellular domain proteins.". Int. Immunol. 18 (3): 473–84. doi:10.1093/intimm/dxh388. PMID 16481347. 
  • Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.". Cell 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. 
  • Kotsis F, Nitschke R, Boehlke C, et al. (2007). "Ciliary calcium signaling is modulated by kidney injury molecule-1 (Kim1).". Pflugers Arch. 453 (6): 819–29. doi:10.1007/s00424-006-0168-0. PMID 17205356. 
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