GSK3A

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Glycogen synthase kinase 3 alpha
Identifiers
Symbol(s)	GSK3A; DKFZp686D0638
External IDs	OMIM: 606784 MGI: 2152453 HomoloGene: 88581
Gene ontology Molecular Function: • nucleotide binding • protein serine/threonine kinase activity • ATP binding • transferase activity Biological Process: • protein amino acid phosphorylation
RNA expression pattern
More reference expression data
Orthologs
	Human	Mouse
Entrez	2931	606496
Ensembl	ENSG00000105723	ENSMUSG00000057177
Uniprot	P49840	n/a
Refseq	NM_019884 (mRNA) NP_063937 (protein)	NM_001031667 (mRNA) NP_001026837 (protein)
Location	Chr 19: 47.43 - 47.44 Mb	Chr 7: 24.94 - 24.95 Mb
Pubmed search	[1]	[2]

Glycogen synthase kinase 3 alpha, also known as GSK3A, is a human gene.

Glycogen synthase kinase 3-alpha (GSK3A; EC {2.7.1.37}) is a multifunctional protein serine kinase, homologous to Drosophila 'shaggy' (zeste-white3) and implicated in the control of several regulatory proteins including glycogen synthase (see GYS1, {138570}) and transcription factors (e.g., JUN, {165160}). It also plays a role in the WNT ({164820}) and PI3K (see PIK3CG, {601232}) signaling pathways (see review by {1:Ali et al. (2001)}).[supplied by OMIM]^[1]

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