GRINL1A

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Glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A
Identifiers
Symbol(s) GRINL1A; DKFZp586F1918
External IDs OMIM: 606485 HomoloGene: 87370
RNA expression pattern

More reference expression data
Orthologs
Human Mouse
Entrez 81488 n/a
Ensembl ENSG00000178620 n/a
Refseq NM_001018102 (mRNA)
NP_001018112 (protein)		 n/a (mRNA)
n/a (protein)
Location Chr 4: 68.59 - 68.59 Mb n/a
Pubmed search [1] n/a

Glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A, also known as GRINL1A, is a human gene.[1]

This gene (GRINL1A) is part of a complex transcript unit that includes the gene for GRINL1A combined protein (Gcom1). Transcription of this gene occurs at a downstream promoter, with at least three different alternatively spliced variants, grouped together as Gdown for GRINL1A downstream transcripts. The Gcom1 gene uses an upstream promoter for transcription and also has multiple alternatively spliced variants.[1]

[edit] References

  1. ^ a b Entrez Gene: GRINL1A glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A.

[edit] Further reading

  • Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.". Gene 138 (1-2): 171–4. PMID 8125298. 
  • Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.". Gene 200 (1-2): 149–56. PMID 9373149. 
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination.". Genome Res. 10 (11): 1788–95. PMID 11076863. 
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing.". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMID 11256614. 
  • Roginski RS, Mohan Raj BK, Finkernagel SW, Sciorra LJ (2001). "Assignment of an ionotropic glutamate receptor-like gene (GRINL1A) to human chromosome 15q22.1 by in situ hybridization.". Cytogenet. Cell Genet. 93 (1-2): 143–4. PMID 11474202. 
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932. 
  • Roginski RS, Mohan Raj BK, Birditt B, Rowen L (2005). "The human GRINL1A gene defines a complex transcription unit, an unusual form of gene organization in eukaryotes.". Genomics 84 (2): 265–76. doi:10.1016/j.ygeno.2004.04.004. PMID 15233991. 
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline.". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMID 15489336. 
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 
  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006.". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMID 16381901. 
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