GPR109A

From Wikipedia, the free encyclopedia

G protein-coupled receptor 109A

Identifiers

GPR109A; PUMAG; Puma-g; HM74a; HM74b

External IDs

OMIM: 609163 MGI: 1933383 HomoloGene: 4391

Gene ontology
Molecular Function:	• rhodopsin-like receptor activity • receptor activity • GTP binding • purinergic nucleotide receptor activity, G-protein coupled
Cellular Component:	• membrane • integral to membrane
Biological Process:	• signal transduction • G-protein coupled receptor protein signaling pathway

Orthologs

Human

Mouse

n/a

n/a

Refseq

NM_177551 (mRNA)
NP_808219 (protein)

NM_030701 (mRNA)
NP_109626 (protein)

Location

n/a

Chr 5: 124.12 - 124.13 Mb

Pubmed search

[1]

[2]

G protein-coupled receptor 109A, also known as GPR109A, is a human gene.^[1]

[edit] References

^ Entrez Gene: GPR109A G protein-coupled receptor 109A.

[edit] Further reading

Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence.". FEBS Lett. 520 (1-3): 97–101. PMID 12044878.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.
Wise A, Foord SM, Fraser NJ, et al. (2003). "Molecular identification of high and low affinity receptors for nicotinic acid.". J. Biol. Chem. 278 (11): 9869–74. doi:10.1074/jbc.M210695200. PMID 12522134.
Soga T, Kamohara M, Takasaki J, et al. (2003). "Molecular identification of nicotinic acid receptor.". Biochem. Biophys. Res. Commun. 303 (1): 364–9. PMID 12646212.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.
Zhang Y, Schmidt RJ, Foxworthy P, et al. (2005). "Niacin mediates lipolysis in adipose tissue through its G-protein coupled receptor HM74A.". Biochem. Biophys. Res. Commun. 334 (2): 729–32. doi:10.1016/j.bbrc.2005.06.141. PMID 16018973.
Tang Y, Zhou L, Gunnet JW, et al. (2006). "Enhancement of arachidonic acid signaling pathway by nicotinic acid receptor HM74A.". Biochem. Biophys. Res. Commun. 345 (1): 29–37. doi:10.1016/j.bbrc.2006.04.051. PMID 16674924.