Gonadal dysgenesis

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Gonadal dysgenesis Classification and external resources
ICD-10	Q99.1
ICD-9	758.6
MeSH	D006059

Gonadal dysgenesis generally refers to a condition where gonadal development is abnormal, often only presenting streaks of connective tissue: so-called streak gonads.

[edit] Causes

The condition may be due to:

• Turner syndrome, and its variations (i.e. mosaicism)
• XX gonadal dysgenesis, also pure gonadal dysgenesis, 46, XX
• Swyer syndrome, also pure gonadal dysgenesis, 46, XY
• Perrault syndrome
• Mixed gonadal dysgenesis
• Endocrine disruptors

[edit] Presentation

It is one of the causes of intersexuality, because the genitalia are determined to be neither exclusively male nor female.

[edit] See also

• Ovotestis

v • d • e Pathology: chromosome abnormalities (Q90-Q99, 758) Autosomal trisomies Down syndrome (21), Edwards syndrome (18), Patau syndrome (13), Trisomy 9, Warkany syndrome 2 (8), Cat eye syndrome (22), Trisomy 22, Trisomy 16 Autosomal monosomies/deletions Wolf-Hirschhorn syndrome (4), Cri du chat (5), Williams syndrome (7), Angelman syndrome/Prader-Willi syndrome (15), Miller-Dieker syndrome/Smith-Magenis syndrome (17), 22q11.2 deletion syndrome (22) X/Y linked Monosomy: Turner syndrome (XO) Trisomy: Triple X syndrome (XXX), Klinefelter's syndrome (XXY), XYY Other Karyotypes: XXXX, XXYY, XXXXX, XXXXY Translocations Philadelphia chromosome, Burkitt's lymphoma Other Fragile X syndrome, Gonadal dysgenesis (Mixed gonadal dysgenesis)