Glycyrrhizinate beta-glucuronidase

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In enzymology, a glycyrrhizinate beta-glucuronidase (EC 3.2.1.128) is an enzyme that catalyzes the chemical reaction

glycyrrhizinate + H₂O 1,2-beta-D-glucuronosyl-D-glucuronate + glycyrrhetinate

Thus, the two substrates of this enzyme are glycyrrhizinate and H₂O, whereas its two products are 1,2-beta-D-glucuronosyl-D-glucuronate and glycyrrhetinate.

This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse O- and S-glycosyl compounds. The systematic name of this enzyme class is glycyrrhizinate glucuronosylhydrolase. Other names in common use include glycyrrhizin beta-hydrolase, glycyrrhizin hydrolase, and glycyrrhizinic acid hydrolase.

[edit] References

• IUBMB entry for 3.2.1.128
• BRENDA references for 3.2.1.128 (Recommended.)
• PubMed references for 3.2.1.128
• PubMed Central references for 3.2.1.128
• Google Scholar references for 3.2.1.128
• Muro, T, Kuramoto T, Imoto K and Okada S (1986). "Purification and some properties of glycyrrhizinic acid hydrolase from Aspergillus niger GRM3". Agric. Biol. Chem. 50: 687–692. 

[edit] External links

The CAS registry number for this enzyme class is 102484-56-0.

• IUBMB entry for 3.2.1.128

• KEGG entry for 3.2.1.128

• BRENDA entry for 3.2.1.128

• NiceZyme view of 3.2.1.128

• EC2PDB: PDB structures for 3.2.1.128

• PRIAM entry for 3.2.1.128

• PUMA2 entry for 3.2.1.128

• IntEnz: Integrated Enzyme entry for 3.2.1.128

• MetaCyc entry for 3.2.1.128

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047967: glycyrrhizinate beta-glucuronidase

• AMIGO entry for GO code 0047967: glycyrrhizinate beta-glucuronidase