Glycoprotein N-palmitoyltransferase

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In enzymology, a glycoprotein N-palmitoyltransferase (EC 2.3.1.96) is an enzyme that catalyzes the chemical reaction

palmitoyl-CoA + glycoprotein CoA + N-palmitoylglycoprotein

Thus, the two substrates of this enzyme are palmitoyl-CoA and glycoprotein, whereas its two products are CoA and N-palmitoylglycoprotein.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl-CoA:glycoprotein N-palmitoyltransferase. This enzyme is also called mucus glycoprotein fatty acyltransferase. This enzyme participates in aminosugars metabolism. This enzyme has at least one effector, Dithiothreitol.

[edit] References

• IUBMB entry for 2.3.1.96
• BRENDA references for 2.3.1.96 (Recommended.)
• PubMed references for 2.3.1.96
• PubMed Central references for 2.3.1.96
• Google Scholar references for 2.3.1.96
• Liau YH, Slomiany BL, Slomiany A, Piasek A, Palmer D, Rosenthal WS (1985). "Identification of mucus glycoprotein fatty acyltransferase activity in human gastric mucosa". Digestion. 32: 57–62. PMID 4018446. 

[edit] External links

The CAS registry number for this enzyme class is 97162-74-8.

• IUBMB entry for 2.3.1.96

• KEGG entry for 2.3.1.96

• BRENDA entry for 2.3.1.96

• NiceZyme view of 2.3.1.96

• EC2PDB: PDB structures for 2.3.1.96

• PRIAM entry for 2.3.1.96

• PUMA2 entry for 2.3.1.96

• IntEnz: Integrated Enzyme entry for 2.3.1.96

• MetaCyc entry for 2.3.1.96

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0018010: glycoprotein N-palmitoyltransferase

• AMIGO entry for GO code 0018010: glycoprotein N-palmitoyltransferase