Glycine N-acyltransferase

From Wikipedia, the free encyclopedia

In enzymology, a glycine N-acyltransferase (EC 2.3.1.13) is an enzyme that catalyzes the chemical reaction

acyl-CoA + glycine $\rightleftharpoons$ CoA + N-acylglycine

Thus, the two substrates of this enzyme are acyl-CoA and glycine, whereas its two products are CoA and N-acylglycine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is acyl-CoA:glycine N-acyltransferase. Other names in common use include glycine acyltransferase, and glycine-N-acylase.

[edit] References

IUBMB entry for 2.3.1.13
BRENDA references for 2.3.1.13 (Recommended.)
PubMed references for 2.3.1.13
PubMed Central references for 2.3.1.13
Google Scholar references for 2.3.1.13
Nandi DL, Lucas SV, Webster LT Jr (1979). "Benzoyl-coenzyme A:glycine N-acyltransferase and phenylacetyl-coenzyme A:glycine N-acyltransferase from bovine liver mitochondria. Purification and characterization". J. Biol. Chem. 254: 7230–7. PMID 457678.
SCHACHTER D, TAGGART JV (1954). "Glycine N-acylase: purification and properties". J. Biol. Chem. 208: 263–75. PMID 13174534.
Webster LT, Siddiqui UA, Lucas SV, Strong JM, Mieyal JJ (1976). "Identification of separate acyl- CoA:glycine and acyl-CoA:L-glutamine N-acyltransferase activities in mitochondrial fractions from liver of rhesus monkey and man". J. Biol. Chem. 251: 3352–8. PMID 931988.