Glycerophospholipid arachidonoyl-transferase (CoA-independent)

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In enzymology, a glycerophospholipid arachidonoyl-transferase (CoA-independent) (EC 2.3.1.147) is an enzyme that catalyzes the chemical reaction

1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine $\rightleftharpoons$ 1-organyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine + 1-organyl-2-lyso-sn-glycero-3-phosphocholine

Thus, the two substrates of this enzyme are 1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine and 1-organyl-2-lyso-sn-glycero-3-phosphoethanolamine, whereas its two products are 1-organyl-2-arachidonoyl-sn-glycero-3-phosphoethanolamine and 1-organyl-2-lyso-sn-glycero-3-phosphocholine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is 1-organyl-2-arachidonoyl-sn-glycero-3-phosphocholine:1-organyl-2-lys o-sn-glycero-3-phosphoethanolamine arachidonoyltransferase (CoA-independent).

[edit] References

IUBMB entry for 2.3.1.147
BRENDA references for 2.3.1.147 (Recommended.)
PubMed references for 2.3.1.147
PubMed Central references for 2.3.1.147
Google Scholar references for 2.3.1.147
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Snyder F, Lee TC, Blank ML (1992). "The role of transacylases in the metabolism of arachidonate and platelet activating factor". Prog. Lipid. Res. 31: 65–86. doi:10.1016/0163-7827(92)90016-C. PMID 1641397.