Glycerophosphoinositol glycerophosphodiesterase

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In enzymology, a glycerophosphoinositol glycerophosphodiesterase (EC 3.1.4.44) is an enzyme that catalyzes the chemical reaction

1-(sn-glycero-3-phospho)-1D-myo-inositol + H₂O myo-inositol + sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are 1-(sn-glycero-3-phospho)-1D-myo-inositol and H₂O, whereas its two products are myo-inositol and sn-glycerol 3-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is 1-(sn-glycero-3-phospho)-1D-myo-inositol glycerophosphohydrolase. Other names in common use include sn-glycero(3)phosphoinositol glycerophosphohydrolase, and sn-glycero-3-phospho-1-inositol glycerophosphohydrolase.

[edit] References

• IUBMB entry for 3.1.4.44
• BRENDA references for 3.1.4.44 (Recommended.)
• PubMed references for 3.1.4.44
• PubMed Central references for 3.1.4.44
• Google Scholar references for 3.1.4.44
• Dawson RM, Hemington N, Richards DE, Irvine RF (1979). "sn-Glycero(3)phosphoinositol glycerophosphohydrolase. A new phosphodiesterase in rat tissues". Biochem. J. 182: 39–49. PMID 40550. 

[edit] External links

The CAS registry number for this enzyme class is 72414-13-2.

• IUBMB entry for 3.1.4.44

• KEGG entry for 3.1.4.44

• BRENDA entry for 3.1.4.44

• NiceZyme view of 3.1.4.44

• EC2PDB: PDB structures for 3.1.4.44

• PRIAM entry for 3.1.4.44

• PUMA2 entry for 3.1.4.44

• IntEnz: Integrated Enzyme entry for 3.1.4.44

• MetaCyc entry for 3.1.4.44

• Atomic-resolution structures of enzymes belonging to this class

[edit] Gene Ontology (GO) codes

• EGO entry for GO code 0047395: glycerophosphoinositol glycerophosphodiesterase

• AMIGO entry for GO code 0047395: glycerophosphoinositol glycerophosphodiesterase